Vascular endothelial growth factor and microvascular density in esophageal and gastric carcinomas

Table 1 Relationship between expression of VEGF and MVD and pathological features of esophageal carcinoma

Pathological characteristics	n	VEGF				MVD
		-	+-++	χ2	P	¯x ± s	P(t)
Degree of differentiation
Well differentiated	27	9	18	7.08	< 0.05	38.52 ± 9.22	< 0.05
Poorly differentiated	32	2	30			43.43 ± 7.61	(t = 2.07)
Depth of invasion
Invading musclaris	37	7	30	0.01	> 0.05	40.38 ± 8.31	> 0.05
Invading serosa	22	4	18			42.53 ± 9.24	(t = 0.88)
LN metastasis
-	35	10	25	5.59	< 0.05	38.22 ± 8.54	< 0.05
+	24	1	24			45.5 ± 7.04	(t = 3.23)

Table 2 Relationship between expression of VEGF and MVD and pathological features of gastric carcinoma

Pathological characteristics	n	VEGF				MVD
		-	+-++	χ2	P	¯x ± s	P (t)
Degree of differentiation
Well differentiated	43	21	22	11.31	< 0.001	32.85 ± 6.14	< 0.01
Poorly differentiated	37	5	32			38.63 ± 5.10	(t = 4.53)
Depth of invasion
Not invading serosa	39	14	25	0.40	> 0.05	34.94 ± 9.26	> 0.05
Invading serosa	41	12	29			33.68 ± 9.12	(t = 0.30)
Tumor stage
Early stage	21	15	6	19.67	< 0.001	32.14 ± 5.89	< 0.05
Progressive stage	59	11	48			35.46 ± 6.58	(t = 2.04)
LN metastasis
-	52	23	29	9.32	< 0.01	33.06 ± 5.33	< 0.05
+	28	3	25			35.74 ± 7.58	(t = 2.07)

Table 3 Relationship between VEGF expression and MVD in the two cancers

	n	MVD
		¯x± s	P(t)
VEGF expression in esophageal carcinoma
-	11	43.45 ± 6.98	< 0.05
+-++	48	31.30 ± 8.74	(t = 4.33)
VEGF expression in esophageal carcinoma
-	26	31.08 ± 9.54	< 0.05
+-++	54	36.83 ± 8.87	(t = 2.65)