Expressions of PCNA, p53, p21WAF-1 and cell proliferation in fetal esophageal epithelia: Comparative study with adult esophageal lesions from subjects at high-incidence area for esophageal cancer in Henan, North China

Table 1 Distribution of fetus sex and age

Sex	Age (months)						Mean age (months)
	4	5	6	7	8	> 9
Male	0	2	4	3	0	0	6.11 ± 0.78
Female	2	5	4	7	3	1	6.36 ± 1.47a
Total	2	7	8	10	3	1	6.29 ± 1.30

^aP > 0.05, t-test, no significant difference was detected in the distribution of age between male and female fetuses.

Table 2 Quantitative comparison of PCNA expression between fetal and subtypes of adult esophageal epithelia

Histopathological subtypes	Case (n)	Number of immunostaining positive cells/mm2
Adult normal	31	200 ± 113
Adult BCH	106	286 ± 150
Fetal	31	506 ± 239a
Adult DYS	31	719 ± 389
Adult SCC	26	1261 ± 545

^aP < 0.05 vs t-test.

Table 3 Comparison of p53 expression between fetal and subtypes of adult esophageal epithelia

Histopathological subtypes	Case (n)	Positive immunostaining
		Number	Percentage (%)
Fetal	31	3	10a
Adult normal	28	14	50
Adult BCH	37	23	62
Adult DYS	11	8	73
Adult SCC	7	6	86

^aP < 0.05 vs Fisher's exact test.