Direct intrahepatic portacaval shunt: An experimental study

Table 1 Portosystemic Gradient before and after DIPS (kPa)

	Pressure of IVC		Pressure of Portal vein		PSG
	Before	After	Before	After	Before	After
	1.28 ± 0.28	1.41 ± 0.28	1.86 ± 0.21	1.57 ± 0.17	0.59 ± 0.20	0.24 ± 0.11
P values	0.034		0.001		0.007

Table 2 Laboratory examination before DIPS, 1, 7 and 14 d after DIPS

Laboratory examination	Pre- DIPS	1 d after DIPS	7 d after DIPS	14 d after DIPS
ALT (U/L)	5.40 ± 0.69	34.20 ± 3.46	18.0 ± 2.11	5.80 ± 0.66
AST (U/L)	16.00 ± 0.79	59.70 ± 2.22	23.90 ± 0.90	17.60 ± 0.75
TB (uoml/L)	1.86 ± 0.20	1.94 ± 023	2.16 ± 0.17	2.10 ± 0.17
CB (uoml/L)	0.66 ± 0.10	0.86 ± 0.14	0.95 ± 0.12	0.88 ± 0.19
BAL (uoml/L)	35.66 ± 4.10	66.94 ± 3.44	36.08 ± 3.93	43.59 ± 3.91

Note: Compared with the value of pre-DIPS the swine's ALT and AST rose significantly 1 and 7 d after DIPS. But 7 d’ value had decreased significantly lower than that of first day after procedure. 14 d after DIPS the swine's ALT and AST returned to their baseline value of pre-DIPS. Swine's TB and CB kept no change before and after DIPS. Animal's blood ammonia level elevated significantly first day after DIPS. 7 d after procedure the animal's BAL returned to its baseline value of pre-DIPS and kept no significant change at 14 d after DIPS.