Correlation of P-glycoprotein expression with poor vascularization in human gallbladder carcinomas

Table 1 Nevin staging system for gallbladder cancer[1]

Stage	Definition
1	Tumor invades mucosa only
2	Tumor invades muscularis and mucosa
3	Tumor invades subserosa, muscularis and mucosa
4	Tumor invades all layers of gallbladder wall plus cystic lymph node
5	Tumor extends into liver bed or distant spread

Table 2 Characteristics of MVC in gallbladder carcinoma

Characteristics	n	MVC
Pathologic types
Papillary adenocacinoma	4	27 ± 8a
Tubal adenocarcinoma	25	35 ± 10a
Mucous adenocarcinoma	3	32 ± 10a
Tumor differentiation
Well	12	28 ± 9b
Moderate-poor	20	37 ± 9b
Nevin staging
S1, S2, S3	14	28 ± 10c
S4, S5	18	38 ± 8c

^aP > 0.05,

^bP < 0.05,

^cP < 0.01.

Table 3 Characteristics of P-gp expression in gallbladder carcinoma

Characteristics	n	+	%
Pathologic types
Papillary adenocacinoma	4	3	75.0a
Tubal adenocarcinoma	25	15	60.0a
Mucous adenocarcinoma	3	2	66.7a
Tumor differentiation
Well	12	9	75.0b
Moderate-poor	20	11	55.0b
Nevin staging
S1, S2, S3	14	11	78.6c
S4,S5	18	9	50.0c

^aP > 0.05,

^bP > 0.05,

^cP > 0.05.