Liver fibrosis in chronic viral hepatitis: An ultrasonographic study

Table 1 Histological results in case group

Inflammation grade (G)	No. subjects	Fibrosis stage (S)	No. subjects
0	0	0	7
1	31	1	54
2	85	2	66
3	85	3	52
4	24	4	46
Total	225		225

Table 2 Univariate analysis of quantitative variables

Variables	Grouped by G		Grouped by G
	F value	P value	F value	P value
PVmax	29.17	< 0.001	19.38	< 0.001
GBT	24.03	< 0.001	14.60	< 0.001
PVD	20.43	< 0.001	18.07	< 0.001
PVmea	18.69	< 0.001	11.28	< 0.001
HVD	16.88	< 0.001	20.21	< 0.001
RPVmax	14.24	< 0.001	7.18	< 0.001
SPL	11.57	< 0.001	14.87	< 0.001
SPVD	9.47	< 0.001	12.76	< 0.001
SPT	9.28	< 0.001	11.18	< 0.001
CI	5.22	< 0.01	3.96	< 0.01
RPVD	5.30	< 0.01	3.43	< 0.01
LLL	2.99	< 0.05	3.41	< 0.05
SPVF	2.72	< 0.05	4.97	< 0.01
SPAD	4.20	< 0.01	2.29	< 0.05

Table 3 Non-parametric analysis of categorical variables

Variables	Grouped by G		Grouped by G
	χ² value	P value	χ² value	P value
LE	50.17	< 0.001	91.34	< 0.001
GBsiz	22.18	< 0.001	21.00	< 0.001
HVW	22.14	< 0.001	33.34	< 0.001
GBsm	20.07	< 0.001	78.99	< 0.001
Lsur	18.31	< 0.001	66.92	< 0.001
U	13.66	< 0.01	32.07	< 0.001
GBst	8.45	< 0.05	6.06	> 0.05

Table 4 Ultrasonographic variables with significant correlation with G and S

	Ultrasonographic variables
Associated with G (22 items)	GBsm, PVmax, GBT, LE, PVD, HVD, PVmea, RPVmax, SPL, SPT, SPVD, HVW, GBsiz, Lsur, CI, RPVD, RPVmea, U, LLL, GBst, SPVF and SPAD
Associated with S (19 items)	GBT, LE, GBsm, PVD, PVmax, Lsur, HVD, PVmea, RPVmax, SPL, SPT, SPVD, HVW, GBsiz, CI, U, LLL, SPVF and RPVD

Table 5 Diagnostic accuracy of ultrasonography and serology for the evaluation of fibrosis degrees (%)

	Mild fibrosis	Moderate fibrosis	Severe fibrosis
Serology	79.5	19.1b	66.7
Ultrasonography	74.5	46.8b	62.5

^bP < 0.01 serology vs ultrasonography.