Pancreatic microcirculatory impairment in experimental acute pancreatitis in rats

Table 1 Intravital fluorescence microscopy of pancreatic microcirculation with FITC-labeled erythrocytes

t/h	Group	d (FITC-RBC)/(× 109 cell/L)	Velocity of FITC-RBC/(cell·min-1)	RBC flow/(nL·min-1)	Microcirculatory blood flow/(nL·min-1)
4	Control	113 ± 5	86 ± 3	0.28 ± 0.01	0.88 ± 0.06
	APb	85 ± 9	43 ± 2	0.12 ± 0.03	0.56 ± 0.09
6	Control	104 ± 4	81 ± 4	0.31 ± 0.02	0.99 ± 0.07
	APb	68 ± 7	36 ± 5	0.09 ± 0.03	0.45 ± 0.12
8	Control	96 ± 6	84 ± 5	0.29 ± 0.04	0.91 ± 0.06
	APb	59 ± 9	30 ± 5	0.07 ± 0.03	0.34 ± 0.10

^bP < 0.001 vs control.

Table 2 Intravital observation of pancreatic microcirculation

t/h	Group	D (arteriole)/μm	D (venule)/μm	D (capillary)/μm	d (Capillary)/cm-1	Capillary perfusion
4	Control	23.5 ± 8	28 ± 3	6.7 ± 1.5	394 ± 7	Stable
	AP	20.2 ± 5.1	29.1 ± 2	7 ± 1.4	381 ± 9	Unstable
6	Control	24.1 ± 8	28 ± 2.7	6.9 ± 1.48	400 ± 5.8	Stable
	AP	16.4 ± 3.1a	27.5 ± 3	6 ± 0.3	291 ± 16a	Intermittent & irregular
8	Control	23.2 ± 5.5	27.4 ± 1.6	7.3 ± 1	349 ± 8	Relatively stable
	AP	18.2 ± 3.5a	29 ± 1.5a	5.2 ± 0.3b	277 ± 13b	Intermittent & irregular

^aP < 0.05,

^bP < 0.001 vs control.