Transforming growth factor-β1 in invasion and metastasis in colorectal cancer

Table 1 Clinicopathologic characteristics of colorectal cancer with expression of TGFβ1 and TGFβRII

Variables		n	TGFβ1-positive n (%)	TGFβRII-positive n (%)
Age (yrs)	≥ 50	60	24 (40.0)	30 (50.0)
	< 50	38	13 (34.2)	16 (42.1)
Sex	Male	53	20 (41.5)	25 (53.7)
	Female	45	17 (31.0)	21 (37.9)
Tumor size	< 5 cm	56	21 (37.5)	24 (42.9)
	≥ 5 cm	42	16 (38.1)	22 (52.4)
Histology
Well-diff. ade		17	9 (52.9)	11 (64.7)
Mode-diff. ade		47	15 (31.9)	19 (40.4)
Poor-diff. ade		34	13 (38.2)	16 (47.1)
Depth of invasion
T1-T2		60	17 (28.3)	33 (55.0)
T3-T4		38	20 (52.6)a	13 (34.2)a
Metastasis	Present	35	18 (51.4)	11 (31.4)
	Absent	63	19 (30.2)a	35 (55.6)a
Stage	A	34	8 (23.5)	23 (67.7)
	B	29	9 (31.1)	13 (44.8)
	C+D	35	20 (57.1)a	10 (28.6)a

^aP < 0.05, T₁-T₂vs T₃-T₄, Present vs Absent, A, B vs C+D