Gastric Cancer
Copyright ©The Author(s) 2002.
World J Gastroenterol. Aug 15, 2002; 8(4): 613-618
Published online Aug 15, 2002. doi: 10.3748/wjg.v8.i4.613
Table 1 Expression of FAK and integrin subunits α5 and β1 in human gastric carcinomas and their relation to clinical and histological variables
FAK
Integrin α5
Integrin β1
-/+++/+++-/+++/+++-/+++/+++
Type of tissues
Unaffected margin specimen4921239843
Gastric carcinoma324353225619
P < 0.01P < 0.01P < 0.01
Differentiation
Poor1430368377
Moderate or well181317141912
P < 0.05P < 0.05P < 0.01
Extent of invasion
Mucosa or superficial stratum133115124
Deep or full stratum194042174415
P < 0.01NSNS
Metastasis
Absent23132610297
Present193027122712
P < 0.01NSNS
Table 2 Expression of FAK and integrin subunits α5 and β1 in human colorectal carcinomas and their relation to clinical and histological variables
FAK
Integrin α5
Integrin β1
-/+++/+++-/+++/+++-/+++/+++
Type of tissues
Unaffected margin specimen4921239843
Gastric carcinoma324353225619
P < 0.01P < 0.01P < 0.01
Differentiation
Poor1430368377
Moderate or well181317141912
P < 0.05P < 0.05P < 0.01
Extent of invasion
Mucosa or superficial stratum133115124
Deep or full stratum194042174415
P < 0.01NSNS
Metastasis
Absent23132610297
Present193027122712
P < 0.01NSNS
Table 3 Expression of FAK and integrin subunits α5 and β1 in human hepatocellular carcinomas and their relation to clinical and histological variables
FAK
Integrin α5
Integrin β1
-/+++/+++-/+++/+++-/+++/+++
Type of tissues
Unaffected margin specimen151313115
Hepatocellular carcinoma412115106
P < 0.01P < 0.01P < 0.01
Differentiation
Poor178071
Moderate or well253445
P < 0.05P < 0.05P < 0.01
Table 4 Expression of FAK and integrin subunits α5 and β1 in human uterocervical carcinomas and their relation to clinical and histological variables
FAK
Integrin α5
Integrin β1
-/+++/+++-/+++/+++-/+++/+++
Type of tissues
Unaffected margin specimen18013599
adenocarcinoma919919
Squamous carcinoma10010091
P < 0.05P < 0.05P < 0.05
Differentiation
Poor9110091
Moderate or well1009191
P < 0.05P < 0.05P < 0.05
Extent of invasion
Mucosa or superficial stratum508041
Deep or full stratum141141141
P < 0.05NSNS