Li XW, Ding YQ, Cai JJ, Yang SQ, An LB, Qiao DF. Studies on mechanism of Sialy Lewis-X antigen in liver metastases of human colorectal carcinoma. World J Gastroenterol 2001; 7(3): 425-430 [PMID: 11819805 DOI: 10.3748/wjg.v7.i3.425]
Corresponding Author of This Article
Professor Yan-Qing Ding, Department of Pathology, The First Military Medical University, Tonghe, Guangzhou 510515, Guangdong Province, China. DYQ@fimmu.edu.cn
Article-Type of This Article
Brief Reports
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Jun 15, 2001; 7(3): 425-430 Published online Jun 15, 2001. doi: 10.3748/wjg.v7.i3.425
Table 1 Expressions of α1,3Fuc-TmRNA in two cell lines
n
-x±s
t
P
Lovo cells
10
21.2055 ± 7.7472
3.537
0.002
HT29 cells
10
10.7922 ± 5.1653
Table 2 Expressions of SLeX antigens in the two cell lines
n
-x±s
t
P
Lovo cells
10
32.7633 ± 10.8716
2.452
0.025
HT29 cells
10
21.9188 ± 8.8016
Table 3 The different adhesive potentials of tumor cells to umbilical vein endothelial cells with the tumor cells sealed
n
Control groups -x±s
Experimental groups -x±s
t
P
Lovo cells
10
213 ± 15.6702
124 ± 16.7319
12.167
0.0001
HT29 cells
10
147 ± 4.5522
69 ± 7.3786
28.632
0.0001
Table 4 Effects of SLex monoclonal antibody on the liver metastases model of experimental nude mice
Lovo cells
HT29 cells
Metastases
No metastases
Metastases
No metastases
Control groups
9
0
4
5
Experimental groups
2
7
1
8
Citation: Li XW, Ding YQ, Cai JJ, Yang SQ, An LB, Qiao DF. Studies on mechanism of Sialy Lewis-X antigen in liver metastases of human colorectal carcinoma. World J Gastroenterol 2001; 7(3): 425-430