Transretinoic acid inhibits rats gastric epithelial dysplasia induced by N-methyl-N-nitro-N-nitrosoguanidine: influences on cell apoptosis and expression of its regulatory genes

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Jun 15, 2001 (publication date) through Nov 3, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 15, 2001; 7(3): 394-398
Published online Jun 15, 2001. doi: 10.3748/wjg.v7.i3.394

Table 1 Histopathological changes and apoptosis of the gastric mucosa

Group	n	Modest dysplasia (n)	Modest and severe dysplasia (n)	Percentage (%)	Apoptoticindex
Normal	15	0	0	0	8.3 ± 3.1
DIM	15	3	11	73.3%	2.2 ± 0.4^a
DIMTR	15	4	4	26.7%^a^b	7.8 ± 2.6^b^c

^aP < 0.05 vs normal;

^bP > 0.05 vs normal;

^cP > 0.05 vs DIM group.

Citation: Cui RT, Cai G, Yin ZB, Cheng Y, Yang QH, Tian T. Transretinoic acid inhibits rats gastric epithelial dysplasia induced by N-methyl-N-nitro-N-nitrosoguanidine: influences on cell apoptosis and expression of its regulatory genes. World J Gastroenterol 2001; 7(3): 394-398
URL: https://www.wjgnet.com/1007-9327/full/v7/i3/394.htm
DOI: https://dx.doi.org/10.3748/wjg.v7.i3.394