Growth hormone stimulates remnant small bowel epithelial cell proliferation

Table 1 Effect of growth hormone on body weight

	Control-transect (n = 10)	Control-resect (n = 10)	GH-resect (n = 10)
Day 0	249 ± 13	251 ± 11	244 ± 10
Day 8	287 ± 11	205 ± 10a	211 ± 11a
Day 29	351 ± 13	297 ± 16a	332 ± 15b

Day 0: before operation; Day 8: 1 week after operation; Day 29: 4 wk after operation. Data are expressed as mean ± SD;

^aP < 0.05, vs control-transect group;

^bP < 0.05, vs control-resect group.

Table 2 Effect of growth hormone on small intestinal mucosal parameters

	Control-transect (n = 10)	Control-resect (n = 10)	GH-resect (n = 10)
Villous height (μm)	180 ± 40	270 ± 40a	340 ± 30b
Crypt depth (μm)	92 ± 17	105 ± 11	120 ± 24a
Mucosal thickness (μm)	320 ± 40	510 ± 80a	520 ± 50a
PI value (%)	3.7 ± 2.0	4.4 ± 1.7	7.6 ± 2.0b
PCNA index (%)	1.6 ± 0.5	3.6 ± 0.6a	8.8 ± 1.1b
C-jun mRNA (%)	10.7 ± 0.7	19.5 ± 2.5	49.2 ± 1.0b

Data are expressed as mean ± SD;

^aP < 0.05, vs control- transect group;

^bP < 0.05, vs control-resect group.