Supra-angular biopsy is more reliable for atrophy recognization: Analysis of 1598 cases for gastric mucosal histological examination

Table 1 Infective rate of Hp evaluated by different site biopsy

	Cases	Hp infective rate (%)
		Antrum	Corpus	Angulus
Normal	76	30 (39.5)	35 (46.1)	31 (40.8)
Superficial gastritis	85	34 (40.0)	42 (49.0)	37 (43.5)
Erosive gastritis	297	160 (53.9)	164 (55.2)	156 (52.5)
Atrophic gastritis	116	90 (77.6)	102 (87.9)	79 (68.1)
Gastric ulcer	467	314 (67.2)	368 (78.8)	326 (69.8)
Gastric carcinoma	74	38	(51.4)	43 (58.1)

Table 2 Infective rate of Hp evaluated by combined biopsies

	Cases	One point (Antrum)	Two points (Antr.corp.)	Three point (Antr.corp.angu)
Normal	76	39 (51.3)	46 (60.5)	47 (61.8)
Superficial gastritis	85	34 (40.0)	46 (54.1)	48 (56.5)
Erosive gastritis	297	160 (57.9)	190 (64.0)	195 (65.7)
Atrophic gastritis	116	90 (77.6)	107 (92.2)	107 (92.2)
Gastric ulcer	467	314 (67.2)	399 (85.4)	406 (86.9)
Gastric carcinoma	74	38 (51.4)	61 (82.4)	64 (86.5)

Table 3 Histological lesions identified in different biopsy sites

	Lesion identified
	Antrum	Corpus	Angulus
Inflammation	1268 (72.9)	1290 (74.1)	1249 (71.8)
Activity	1039 (59.7)	1148 (65.9)	1071 (61.6)
Atrophy*	130 (26.6)	96 (19.6)	320 (65.4)a
Intest.metaplasia	455 (26.1)	137 (17.7)	554 (31.8)a

^* only 1292 cases in all three points judgable included.

^aP < 0.05, vs the results of antrum and corpus.

Table 4 The accuracy of endoscopical atrophy

Endoscopy atrophy	Cases	Evaluation by separate point
		Antrum	Corpus	Angulus
Negative	106	10 (9.4)	9 (8.5)	15 (14.2)
Suspected	697	124 (17.8)	47 (6.7)	171 (24.5)
Positive	487	108 (22.2)	77 (15.8)	235 (48.3)
+	252	47 (18.7)	36 (14.3)	103 (40.
++	201	46 (22.9)	35 (17.4)	107 (53.2)
+++	36	15 (41.7)	6 (16.7)	27 (69.2)

Table 5 The occurrence of histological atrophy in different diseases

Endoscopic diagnosis	Cases	Histological atrophy (%)
		Antrum	Corpus	Angulus
Normal	69	6 (8.7)	5 (7.2)	15 (21.7)
Superficial gastritis	79	15 (18.9)	8 (10.1)	23 (29.1)
Flat erosion	152	26 (17.1)	5 (3.3)	33 (21.7)
Elevated erosion	119	29 (24.4)	7 (5.9)	39 (32.7)
Atrophic gastritis	107	59 (55.1)	35 (32.7)	88 (82.2)
Gastric ulcer	387	134 (34.6)	39 (10.1)	175 (45.2)
Duodenal ulcer	135	36 (26.7)	8 (5.9)	47 (34.8)
Gastroduodenal ulcer	64	21 (32.8)	5 (7.8)	28 (43.8)
Hyperplastic polyp	111	14 (12.6)	8 (7.2)	33 (29.7)
Adenoma	11	3 (27.3)	3 (27.3)	6 (54.5)
Carcinoma	46	22 (47.8)	6 (13.4)	27 (58.7)
Submucosal tumors	12	3 (25.0)	2 (16.7)	3 (25.0)