Transfusion transmitted virus infection in general populations and patients with various liver diseases in south China

Table 1 Prevalence of TTV infection among study cohorts

Groups	TTV positive rate (n)	TTV negative rate (n)	Total
Rural population	10.61 (19)	89.39 (160)	179
Cryptogenic hepatitisa	38.63 (17)	61.37 (27)	44
HBsAg asymptomatic carrier	9.62 (5)	90.38 (47)	52
Chronic hepatitis Bb	15.22 (7)	84.78 (39)	46
HBV related active liver cirrhosisc	22.5 (9)	77.5 (31)	40
HBV related hepatic failured	23.08 (9)	76.92 (30)	39
Hepatocyte carcinomae	9.52 (2)	90.48 (19)	21
Total	16.15 (68)	83.85 (353)	421

^aχ² = 20.486, P < 0.005 vs rural population;

^bχ² = 0.713, P > 0.25 vs HBsAg asymptomatic carrier;

^cχ² = 0.749, P > 0.25 vs chronic hepatitis B;

^dχ² = 0.853, P > 0.25 vs chronic hepatitis B;

^eχ² = 0.000, P > 0.9 vs HBsAg asymptomatic carrier.

Table 2 The prevalence of TTV infection in a natural village in Yunnan Province, regarding of sex, nationality and age

Result	Sexa			Nationalityb			Agec
	Male	Female	Total	Han	Yi	Total	< 14	14-55	> 55	Total
TTV positive	7	12	19	8	11	19	5	13	1	19
TTV negative	83	77	160	82	78	160	47	102	11	160
Total	90	89	179	90	89	179	52	115	12	179
Prevalence (%)	7.8	13.5	10.6	8.9	12.4	10.6	9.6	11.3	8.3	10.6

^aχ² = 1.535, P > 0.2;

^bχ² = 0.568, P > 0.4; ^cχ² = 0.178, P > 0.9.

Table 3 Effect on liver function test of TTV co-infection in patients with chronic hepatitis B

Liver function test	TTV negative	TTV positive	t value	P value
ALT (U/L)	347.0 ± 286.5	282.3 ± 230.2	0.523	> 0.5
AST (U/L)	199.9 ± 171.8	140.8 ± 105.3	0.742	> 0.2
Protein A/G	1.24 ± 0.28	1.26 ± 0.12	0.140	> 0.5
TBil (μmol/L)	34.1 ± 30.6	22.8 ± 9.3	0.883	> 0.2
Prothrombin (s)	17.7 ± 5.5	15.6 ± 1.53	0.783	> 0.2