Chemopreventive effect of oltipraz on AFB1-induced hepatocarcinogenesis in tree shrew model

Table 1 The number and size of γ-GT positive hepatocyte-group (x^-± s_x-)

Group	Treatment	No./cm2	mm2/cm2	mm2/No.
A	Normal control	167.29 ± 50.47	2.90 ± 1.01	0.017 ± 0.002
B	AFB1	71.92 ± 42.19a	1.14 ± 0.69a	0.015 ± 0.002
C	AFB1 + OLT daily	167.10 ± 45.94cd	2.73 ± 0.87cd	0.016 ± 0.001
D	AFB1 + OLT weekly	83.66 ± 34.94a	1.33 ± 0.86a	0.015 ± 0.002b

t test:

^aP < 0.05,

^bP < 0.01, vs group A;

^cP < 0.01, vs group B;

^dP < 0.01, vs group D. OLT: Oltipraz; No./cm²: The number of γ-GT positive hepatocyte-group per cm² of liver tissue; mm²/cm²: mm² of γ-GT positive hepatocyte-group per cm² of liver tissue; mm²/No.: mm² of γ-GT positive hepatocyte-group per each one.