Pathogenetic effects of platelet activating factor on enterogenic endotoxemia after burn

Table 1 Levels of PAF in blood and intestinal tissue (^-x±s)

Group	n		After burn (h)
			6	12	24	48
Control	10
Blood (μg/L)		0.56 ± 0.07
Intestine (ng/g)		0.41 ± 0.06
Burn	40
Blood (μg/L)			1.72 ± 0.21b	2.76 ± 0.25b	1.54 ± 0.24 b	1.19 ± 0.13b
Intestine (ng/g)			1.80 ± 0.21b	2.34 ± 0.18b	1.68 ± 0.15b	1.42 ± 0.16b
Treatment	40
Blood (μg/L)			0.84 ± 0.16da	1.46 ± 0.27db	0.93 ± 0.18ca	0.71 ± 0.15c
Intestine (ng/g)			0.67 ± 0.07da	1.24 ± 0.13db	0.83 ± 0.12da	0.64 ± 0.08da

^aP < 0.05,

^bP < 0.01 vs control;

^cP < 0.05,

^dP < 0.01 vs burn group.

Table 2 Changes of intestinal mucosal permeability (mL·min^-1·100 g^-1, ^-x±s)

Group	n		After burn (h)
			6	12	24	48
Control	10	0.07 ± 0.02
Burn	40		0.33 ± 0.14b	0.58 ± 0.18b	0.21 ± 0.07b	0.13 ± 0.04b
Treatment	40		0.19 ± 0.05db	0.27 ± 0.06db	0.10 ± 0.04da	0.08 ± 0.03c

^aP < 0.05,

^bP < 0.01 vs control;

^cP < 0.05,

^dP < 0.01 vs burn group.

Table 3 Levels of plasma endotoxin (ng/L, ^-x±s)

Group	n		After burn (h)
			6	12	24	48
Control	10	34 ± 8
Burn	40		93 ± 28b	129 ± 32b	90 ± 22b	59 ± 16b
Treatment	40		57 ± 15ca	66 ± 13db	50 ± 10da	43 ± 8c

^aP < 0.05,

^bP < 0.01 vs control,

^cP < 0.05,

^dP < 0.01 vs burn group.