Brief Reports
Copyright ©The Author(s) 2000.
World J Gastroenterol. Apr 15, 2000; 6(2): 304-306
Published online Apr 15, 2000. doi: 10.3748/wjg.v6.i2.304
Table 1 Effect of gastrin on protein kinase C activation (mean ± SD)
Protein kinase C (pmol•min•mg protein)
CytosolMembrane
Control2.39 ± 1.301.07 ± 0.28
Gastrin (25 mg/L)0.91 ± 0.34a2.65 ± 1.21a
Gastrin (25 mg/L) + proglumide (32 mg/L)2.30 ± 0.611.05 ± 0.20
Table 2 Time-dependent effect of gastrin on protein kinase C activation
Protein kinase C (pmol•min•mg protein)
CytosolMembrane
Control2.39 ± 1.301.07 ± 0.28
PG (25 mg/L)
1 min0.91 ± 0.34a2.65 ± 1.21a
2 min1.44 ± 0.341.87 ± 0.57a
5 min2.28 ± 0.490.98 ± 0.18