Tumor growth inhibition effect of hIL-6 on colon cancer cells transfected with the target gene by retroviral vector

Table 1 IL-6 effects on colony formation of HT-29 cells on soft agar

Cell	n	Number of colonies					χ	Colony formation
		1	2	3	4	5
HT-29	5.0	86.0	89.0	92.0	80.0	97.0	84.2	4.21
HTIL-6	5.0	42.0	52.0	41.0	39.0	47.0	44.2	2.21a

^aP < 0.05, rS.

Table 2 Growth sequel of transplantation tumors

Group	Nude mice number	Number of tumor-bearing mice	The time of tumor presentation (days)	Tumor size (mm)	Growth rate (mm/day)
HT-29	5	5	8	20.8	0.65
HT-29pZIP	5	5	8.5	18.2	0.57
HT-29IL-65		4	13.5	8.5b	0.48
Recombinan t virus	5	5	8	6.5b	0.15b

^bP < 0.01, in comparison with HT-29 cell group.