Protective effect of early enteral feeding on postburn impairment of liver function and its mechanism in rats

Table 1 The effects of EEF on the postburn changes of plasma ALT, AST activities and TB, DB contents (^-x ± s)

Group (samples)	Postburn hours
	3	6	12	24	48
EEF (40)
ALT (mmol·s-1/L)	1.21 ± 0.07bd	1.54 ± 0.14bd	1.75 ± 0.17bd	1.39 ± 0.09bd	1.09 ± 0.09bd
AST (mmol·s-1/L)	8.58 ± 0.64bd	11.47 ± 0.81bd	14.30 ± 1.04bd	9.75 ± 0.80bd	7.24 ± 0.65bd
TB (mmol/L)	16.85 ± 2.01ad	14.97 ± 2.36d	12.90 ± 2.01ad	10.82 ± 1.71bd	6.59 ± 1.61b
DB (mmol/L)	7.72 ± 1.90d	4.68 ± 1.46bd	2.42 ± 0.78b	1.72 ± 0.36b	1.74 ± 1.09b
Burn (40)
ALT (mmol·s-1/L)	2.06 ± 0.13d	2.90 ± 0.19d	3.19 ± 0.23d	2.99 ± 0.17d	2.21 ± 0.14d
AST (mmol·s-1/L)	12.20 ± 0.77d	18.77 ± 0.84d	23.13 ± 1.14d	16.18 ± 0.94d	12.56 ± 1.00d
TB (mmol/L)	19.26 ± 2.97d	16.98 ± 2.11d	15.08 ± 2.37d	18.32 ± 2.69d	10.82 ± 1.97d
DB (mmol/L)	8.26 ± 2.17d	9.77 ± 2.02d	5.50 ± 1.32d	7.10 ± 1.43d	3.54 ± 0.94d
Control (40)
ALT (mmol·s-1/L)	0.61 ± 0.09	0.57 ± 0.07	0.63 ± 0.08	0.58 ± 0.07	0.64 ± 0.10
AST (mmol·s-1/L)	1.55 ± 0.10	1.64 ± 0.09	1.60 ± 0.10	1.71 ± 0.11	1.58 ± 0.10
TB (mmol/L)	5.63 ± 1.41	6.04 ± 1.27	5.81 ± 1.62	6.17 ± 1.02	5.76 ± 1.38
DB (mmol/L)	1.62 ± 0.56	1.46 ± 0.39	1.55 ± 0.42	1.73 ± 0.41	1.53 ± 0.47

^aP < 0.05,

^bP < 0.01 vs burn group;

^dP < 0.01 vs control.

Table 2 The effects of EEF on the postburn changes of plasma total p rotein and albumin levels (c/g·L^-1, ^-x ± s)

Group (samples)	Postburn hours
	3	6	12	24	48
EEF (40)
Total protein	43.10 ± 2.31d	42.49 ± 3.00d	47.61 ± 4.39c	58.33 ± 2.93b	62.36 ± 4.18bd
Albumin	19.32 ± 1.34d	19.49 ± 1.63ad	22.76 ± 2.19d	25.70 ± 2.40b	26.77 ± 1.25b
Burn (40)
Total protein	43.54 ± 2.51d	44.79 ± 2.03d	44.80 ± 3.63d	48.84 ± 4.30d	52.77 ± 1.45
Albumin	19.78 ± 2.11d	20.99 ± 1.23d	21.54 ± 1.72d	21.84 ± 1.84c	22.50 ± 0.83d
Control (40)
Total protein	53.67 ± 2.43	57.41 ± 1.83	52.55 ± 2.62	55.76 ± 3.18	53.92 ± 2.88
Albumin	25.38 ± 1.62	25.72 ± 1.38	26.08 ± 1.72	24.46 ± 1.33	25.64 ± 1.43

^aP < 0.05,

^bP < 0.01 vs burn group;

^cP < 0.05,

^dP < 0.01 vs control.

Table 3 The effects of EEF on the postburn changes of gastric intram ucosal pH (^-x ± s)

Group	Samples	Postburn hours
		3	6	12	24	48
EEF	50	7.119 ± 0.078ab	6.943 ± 0.089ab	7.074 ± 0.037ab	7.285 ± 0.098a	7.257 ± 0.077ab
Burn	50	7.017 ± 0.037b	6.826 ± 0.049b	6.802 ± 0.080b	6.949 ± 0.082b	7.074 ± 0.041b
Control	50	7.321 ± 0.054	7.296 ± 0.067	7.296 ± 0.067	7.306 ± 0.069	7.348 ± 0.074

^aP < 0.01 vs burn group;

^bP < 0.01 vs control.

Table 4 The effects of EEF on the postburn changes of portal endotox in level (Eu/mL, ^-x ± s)

Group	Samples	Postburn hours
		3	6	12	24	48
EEF	40	0.683 ± 0.072ab	0.797 ± 0.085ab	0.542 ± 0.078ab	0.725 ± 0.061ab	0.461 ± 0.049ab
Burn	40	1.394 ± 0.126b	1.518 ± 0.173b	1.124 ± 0.133b	1.627 ± 0.215b	1.168 ± 0.188b
Control	40	0.206 ± 0.032	0.195 ± 0.043	0.189 ± 0.049	0.204 ± 0.037	0.215 ± 0.051

^aP < 0.01 vs burn group;

^bP < 0.01 vs control.

Table 5 The effects of EEF on the postburn changes of plasma TNF-α level (ng/mL, ^-x ± s)

Group	Samples	Postburn hours
		3	6	12	24	48
EEF	40	1.48 ± 0.38ab	2.57 ± 0.45ab	2.36 ± 0.47ab	1.92 ± 0.26ab	1.68 ± 0.45ab
Burn	40	1.92 ± 0.19b	4.49 ± 0.47b	3.51 ± 0.45b	4.07 ± 0.71b	3.24 ± 0.61b
Control	40	0.83 ± 0.08	0.78 ± 0.11	0.83 ± 0.12	0.81 ± 0.09	0.81 ± 0.09

^aP < 0.01 vs burn group;

^bP < 0.01 vs control.