Elevated basal intestinal mucosal cytokine levels in asymptomatic first-degree relatives of patients with Crohn’s disease

Table 1 Study population: demoaraphic data

Clinical data	Control group	First degree relative
Number (n)	10	9
Mean age (Range)	64.3 (40-82)	50.1 (21-79)
Males	4	2
Females	6	7
Indications
Anemia	1	None
Abdominal pain	1	Pain/Weight loss (1)
Guaiac (+)	3	None
Surveillance	5	None
Study	0	3
IBS	0	3
Endoscopic findings
Normal	5	6
Hemorrhoids	3	3
Polyps	2	None
Family His of colitis	None	All
History of IBD	None	None

Table 2 Demographics of Crohn’s disease patients (n = 8)*

Clinical data	Number
Mean age	44 (26.93)
Males	2
Females	6
Extent of the disease
Ileum and colon	5
Ileum alone	2
Colon alon	1
Duration of the disease
<10yrs	1
10-30yrs	6
>30yrs	1
Present medications
6MP, steroids, ASA	4
ASA, steroids	2
ASA	1
None	1
History of Surgery
Yes	6
No	2
Number of first degree relatives
One relative	7
Two relatives	1

ASA = Aminosalicylic acid: 6MP-6 Mercaptopurine ^*One of the patients had two first-degree relatives.