Experimental study of “Tong Xia” purgative method in ameliorating lung injury in acute necrotizing pancreatitis

Table 1 Cell changes in BALF (^-x ± s, × 10⁹/L)

Group	Total cell count	Differential count
		Polymorphonuclear	Mononuclear-macrophage	Other
Saline	36.4 ± 8.2ac	3.1 ± 1.2ac	11.2 ± 3.5a	22.1 ± 7.6
“Tong Xia”	20.7 ± 10.3b	0.8 ± 0.2b	5.3 ± 2.3	14.6 ± 6.3
Sham operation	7.2 ± 4.1	0.2 ± 0.07	4.2 ± 2.3	2.80 ± 1.8

^aP < 0.01,

^bP < 0.05 vs sham operation ;

^cP < 0.05 vs“Tong Xia”.

Table 2 Protein content and TNF activity in BALF (^-x ± s)

Group	TNF activity (IU/mL)	Protein content
Saline	58.75 ± 4.65ab	2.53 ± 0.83ac
“Tong Xia”	49.00 ± 1.83a	1.42 ± 0.31
Sham operation	17.00 ± 0.82	0.93 ± 0.21

^aP < 0.01 vs sham operation;

^bP < 0.01 ,

^cP < 0.05 vs“Tong Xia”.

Table 3 Lung wet/dry weight ratio (^-x ± s)

Group	Lung wet/dry ratio
Saline	4.23 ± 0.74ab
“Tong Xia”	3.24 ± 0.34
Sham operation	2.80 ± 0.17

^aP < 0.01, vs sham operation;

^bP < 0.05, ^cP < 0.05, vs“Tong Xia”.

Table 4 The pancreatic and pulmonary lesions

Group	Number	Pancreatic lesion				Pulmonary lesion
		Negative	Mild	Moderate	Severe	0	I	II	III
Saline	5			2	3		1	3	1
“Tong Xia”	5			3	2		4	1
Sham operation	4	4				4