Relation between HLA-DQA1 genes and genetic susceptibility to duodenal ulcer in Wuhan Hans

Table 1 Distribution of DQA1 allele frequency in duodenal ulcer pati ents and healthy controls from Wuhan Hans

HLA-DQA1 alleles	Controls (n = 50)			DU (n = 70)
	PN	PF	AF	PN	PF	AF
0101	10	0.20	0.11	9	0.13	0.07
0102	13	0.26	0.14	6	0.09a	0.05
0103	8	0.16	0.08	12	0.17	0.09
0201	7	0.14	0.07	10	0.14	0.07
0301	18	0.36	0.20	45	0.64b	0.40
0401	2	0.04	0.02	1	0.01	0.01
0501	12	0.24	0.13	22	0.31	0.17
0601	7	0.14	0.07	12	0.17	0.09

PN: positive number; PF: phenotype frequency; AF: allele frequency. Compared with controls:

^aP = 0.012, RR = 0.27, P_corret > 0.05;

^bP = 0.003, RR = 3.2, P_corret < 0.05.