Inhibitory activity of polysaccharide extracts from three kinds of edible fungi on proliferation of human hepatoma SMMC-7721 cell and mouse implanted S180 tumor

Table 1 The effects of polysaccharide extracts on the MI of SMMC-7721 cells

Groups	MI (%)	P value
C1	18.2 ± 1.1
C2	13.4 ± 1.2
E1	5.8 ± 0.7	< 0.005
E2	8.5 ± 0.9	< 0.005
E3	8.4 ± 0.8	< 0.005

C1: 10% FCS; C2: Non-FCS; E1: 50 mg/L polysaccharide extracts from LE; E2: 50 mg/L polysaccharide extracts from FV; E3: 50 mg/L polysaccharide extracts from AB.

Table 2 The inhibitions of polysaccharide extracts on the proliferation of S-180 implanted tumor in vivo

Groups	n	Dose (mg/kg)	Tumor weight (g)	Inhibition (%)	P value	Mean inhibition (%)
LE 1	10	24	0.369 ± 0.058	55.5	< 0.005	52.8
LE 2	10	24	0.387 ± 0.069	53.3	< 0.005
LE 3	10	24	0.417 ± 0.085	49.7	< 0.005
FV 1	10	24	0.371 ± 0.034	55.3	< 0.005	56.6
FV 2	10	24	0.348 ± 0.039	58.1	< 0.005
FV 3	10	24	0.376 ± 0.044	54.7	< 0.005
AB 1	10	24	0.379 ± 0.049	54.3	< 0.005	51.9
AB 2	10	24	0.39 ± 0.067	53	< 0.005
AB 3	10	24	0.427 ± 0.087	48.5	< 0.005
Control	20		0.83 ± 0.17