Copyright
©The Author(s) 1999.
World J Gastroenterol. Jun 15, 1999; 5(3): 228-230
Published online Jun 15, 1999. doi: 10.3748/wjg.v5.i3.228
Published online Jun 15, 1999. doi: 10.3748/wjg.v5.i3.228
Table 1 Apolipoprotein E phenotype distributions and allele frequenc ies in patients with gallstones and controls
| Groups | n | Phenotype | Allele | |||||
| E2/3(%) | E2/4(%) | E3/3(%) | E3/4(%) | ε2(%) | ε3(%) | ε4(%) | ||
| Patients | 87 | 10(11.4) | 0 | 69(79.4) | 8(9.2) | 5.8 | 89.6 | 4.6 |
| Male | 39 | 4(10.2) | 0 | 31(79.4) | 4(10.2) | 5.1 | 89.8 | 5.1 |
| Female | 48 | 6(12.5) | 0 | 38(79.1) | 4(8.9) | 6.3 | 89.6 | 4.2 |
| Controls | 50 | 5(10.0) | 2(4.0) | 37(74.1) | 6(12.0) | 7.0 | 85.0 | 8.0 |
| Male | 27 | 3(10.0) | 1(3.7) | 20(74.0) | 3(11.0) | 7.4 | 85.2 | 7.4 |
| Female | 23 | 2(8.6) | 1(4.3) | 17(74.6) | 3(13.0) | 6.5 | 84.8 | 8.7 |
Table 2 Comparisons of lipid levels in E2/2, E3/3, E3/4 both gallstone patients and controls
| Lipids (mmol/L) | E2/3 | E3/3 | E3/4 | |||
| Patients (n = 10) | Controls (n = 5) | Patients (n = 69) | Controls (n = 37) | Patients (n = 8) | Controls (n = 6) | |
| TG | 1.43 ± 0.35a | 1.06 ± 0.10 | 0.97 ± 0.21 | 0.64 ± 0.44 | 1.11 ± 0.33 | 0.92 ± 0.16 |
| TC | 2.99 ± 0.65 | 2.52 ± 0.53 | 3.14 ± 0.59 | 3.67 ± 0.76 | 3.94 ± 0.45 | 3.62 ± 0.63 |
| LDL-C | 1.41 ± 0.56a | 2.04 ± 0.16 | 1.87 ± 0.49 | 2.43 ± 0.67 | 1.92 ± 0.64 | 2.46 ± 0.32 |
| VLDL-C | 0.68 ± 0.26a | 0.48 ± 0.20 | 0.46 ± 0.20 | 0.30 ± 0.11 | 0.42 ± 0.13 | 0.44 ± 0.10 |
| HDL-C | 0.95 ± 0.23 | 1.02 ± 0.15 | 0.89 ± 0.30a | 1.28 ± 0.23 | 0.86 ± 0.21 | 0.90 ± 0.36 |
| HDL2-C | 0.53 ± 0.13 | 0.62 ± 0.22 | 0.49 ± 0.18b | 0.73 ± 0.13 | 0.44 ± 0.19 | 0.55 ± 0.18 |
| HDL3-C | 0.42 ± 0.12 | 0.56 ± 0.28 | 0.39 ± 0.12b | 0.55 ± 0.11 | 0.40 ± 0.13 | 0.46 ± 0.12 |
Table 3 The comparisons of lipid levels in E3/3 same gender ei ther gallstone patients or controls
| Lipids (mmol/L) | Male | Female | ||
| Patients (n = 31) | Controls (n = 20) | Patients (n = 38) | Controls (n = 17) | |
| TG | 0.85 ± 0.50 | 0.53 ± 0.22 | 1.10 ± 0.30 | 0.72 ± 0.57 |
| TC | 3.05 ± 0.44 | 0.41 ± 0.57 | 3.23 ± 0.85 | 3.87 ± 0.63 |
| LDL-C | 1.86 ± 0.68 | 2.71 ± 0.49 | 1.89 ± 0.86 | 2.20 ± 0.56 |
| VLDL-C | 0.40 ± 0.24 | 0.25 ± 0.10 | 0.52 ± 0.14 | 0.35 ± 0.17 |
| HDL-C | 0.94 ± 0.33 | 1.21 ± 0.28 | 0.82 ± 0.27b | 1.33 ± 0.19 |
| HDL2-C | 0.52 ± 0.22 | 0.69 ± 0.16 | 0.46 ± 0.15b | 0.77 ± 0.10 |
| HDL3-C | 0.42 ± 0.12 | 0.52 ± 0.13 | 0.36 ± 0.12b | 0.57 ± 0.10 |
- Citation: Lin QY, Du JP, Zhang MY, Yao YG, Li L, Cheng NS, Yan LN, Xiao LJ. Effect of apolipoprotein E gene Hha I restricting fragment length polymorphism on serum lipids in cholecystolithiasis. World J Gastroenterol 1999; 5(3): 228-230
- URL: https://www.wjgnet.com/1007-9327/full/v5/i3/228.htm
- DOI: https://dx.doi.org/10.3748/wjg.v5.i3.228