Comparison of serum Zn, Cu and Se contents between healthy people and patients in high, middle and low incidence areas of gastric cancer of Fujian Province

Table 1 Sample number of different groups among the three areas

Area of incidence	County	Healthy (group I)	Gastric cancer (group II)	Other tumor (group III)
High	Changle	100	41	3
	Putian	52	39	14
Middle	Shaxian	95	14	15
Low	Fuan	49	15	16
Total		296	109	48

Table 2 Serum contents of trace elements in healthy group in high, middle and low gastric cancer incidence areas (^-x±s)

	n	Zn(mg/L)	Cu(mg/L)	Se(μg/L)	Cu/Zn
High (I)	152	0.886 ± 0.015	0.911 ± 0.015	84.82 ± 2.18	1.065 ± 0.025
Middle (II)	95	0.885 ± 0.015	0.942 ± 0.019	84.57 ± 1.23	1.099 ± 0.035
Low (III)	152	1.002 ± 0.019	0.867 ± 0.032	76.87 ± 3.22	0.867 ± 0.033
Analysis of variance		F = 9.326	F = 2.479	F = 2.297	F = 9.939
		P = 0.00012	P = 0.086	P = 0.102	P = 0.000066
Newmen-Keul test in	I:III	q = 5.782a			q = 6.827a
comparison of different	I:II	q = 0.0303			q = 0.955
areas	II:III	q = 5.456a			q = 6.105a

^aP < 0.01.

Table 3 Contents of Zn, Cu and Se in sera of healthy, gastric cancer and other tumor groups (^-x±s)

	n	Zn(mg/L)	Cu(mg/L)	Se(μg/L)	Cu/Zn
Healthy (I)	294	0.905 ± 0.010	0.914 ± 0.011	83.22 ± 1.32	1.044 ± 0.018
Gastric cancer (II)	109	0.843 ± 0.019	1.045 ± 0.023	73.58 ± 1.68	1.308 ± 0.035
Other tumor (III)	48	0.858 ± 0.028	1.127 ± 0.040	75.29 ± 2.33	1.404 ± 0.078
Analysis of variance		F = 5.137	F = 29.168	F = 9.278	F = 35.220
		P = 0.006	P < 0.00001	P = 0.000073	P < 0.000001
Newmen-Keul test in	I:III	q = 4.305a	q = 7.660b	q = 5.852b	q = 9.423b
comparison of different	I:II	q = 2.362b	q = 8.949b	q = 3.426a	q = 9.113b
groups	II:III	q = 0.673	q = 3.094	q = 0.664	q = 2.673