Transduction of Fas gene or Bcl-2 antisense RNA sensitizes cultured drug resistant gastric cancer cells to chemotherapeutic drugs

Table 1 Survival rates of transfectants and non-transfectants treated with chemotheraputic drugs (%)

Cells	n	CDDP (mg/L)			5-FU(mg/L)			VCR(mg/L)
		5	50	500	35	350	3500	0.5	5	50
SGC7901 Fas/VCR	10	45.1a	40.5a	32.0	43.5a	38.6a	30.7a	55.0	46.7a	40.0a
SGC7901 anti-Bcl-2/VCR	10	50.2a	45.1a	40.5	50.1a	44.6a	39.5a	60.3	55.1a	49.2a
SGC7901/VCR	10	70.2	61.3	52.0	71.1	62.2	55.3	72.5	67.4	60.1

In comparison with SGC7901/VCR cells group,

^aP < 0.05.