Bile acids in serum and bile of patients with cholesterol gallstone

Table 1 Changes of serum bile acids in the two groups (μmol/L, ^-x±s_x)

Bile acids	Group with calculi (n = 151)	Control group (n = 256)
DCA1	0.955 ± 0.078	0.696 ± 0.047
CDCA	2.535 ± 0.304	2.084 ± 0.141
CA	1.202 ± 0.134	1.211 ± 0.147
TBA	4.692 ± 0.432	3.290 ± 0.267

¹P = 0.002.

Table 2 Mole percent of serum bile acids in the two groups (%,^-x±s_x)

Bile acids	Group with calculi (n = 151)	Control group (n = 256)	P
DCA	28.12 ± 1667	23.03 ± 1.04	0.007
CDCA	45.11 ± 2.01	52.40 ± 1.32	0.001
CA	27.51 ± 1.93	24.77 ± 1.09	> 0.05
DCA/CDCA	1.76 ± 0.30	0.92 ± 0.14	0.004

Table 3 Correlation between bile acids and biliary CSI (n = 90)

Bile acids	Correlation coefficient	P
LCA	0.288	0.006
DCA	0.311	0.003
CDCA	-0.269	0.01
CA	-0.101	> 0.05

Table 4 Biliary and serum bile acids (n = 90, ^-x±s_x)

Bile acids	Bile (mmol/L)	Serum (μmol/L)	Correlation coefficient1
LCA	1.97 ± 0.18
DCA	24.80 ± 2.12	1.08 ± 0.11	0.12
CDCA	76.93 ± 4.01	2.35 ± 0.43	0.07
CA	40.27 ± 3.08	1.31 ± 0.19	-0.09
TBA	143.97 ± 7.33	4.65 ± 0.62	-0.07

¹P > 0.05

Table 5 Correlation between mole percent of biliary and serum bile acids (n = 90, ^-x±s_x)

Bile acids	Bile(mole %)	Serum (mole %)	Correlation coefficient	P
LCA	1.89 ± 0.24
DCA	17.52 ± 1.06	30.15 ± 2.59	0.445	< 0.001
CDCA	54.16 ± 1.12	36.66 ± 2.91	0.434	< 0.001
CA	26.43 ± 0.96	33.19 ± 3.04	0.313	0.003