Fan J, Ten GJ, He SC, Guo JH, Yang DP, Weng GY. Arterial chemoembolization for hepatocellular carcinoma. World J Gastroenterol 1998; 4(1): 33-37 [PMID: 11819226 DOI: 10.3748/wjg.v4.i1.33]
Corresponding Author of This Article
Dr. Jian Fan, Department of General Surgery, First Affiliated Hospital of Nanjing Railway Medical College, 87 Dingjiaqiao Road, Nanjing 210009, Jiangsu Province, China
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Original Articles
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World J Gastroenterol. Feb 15, 1998; 4(1): 33-37 Published online Feb 15, 1998. doi: 10.3748/wjg.v4.i1.33
Table 1 Clinical characteristcs of patients with hepatocellular carcinoma
Average age in year (range)
49 (24-69)
Sex (male: female)
72:8
Serum AFP level (μmol/L)
< 50
18 (22.5%)
50-399
20 (25%)
> 400
42 (52.5%)
HBsAg+
62 (77.5%)
TBILT(mg/L)
16.9 ± 6.0
ALT(u/L)
68.9 ± 36.6
ALB(g/L)
38.4 ± 4.4
Child’s grade (a:b:c)
30:47:3
Stage (I:II:III:IV)
2:6:62:10
Table 2 Mean doses of embolic agents and anticancer drugs
TSCTV courses
No of patients
Embolic agents
Anticancer drugs
SBMs (mg)
LUF (mL)
SB (mg)
ACR (mg)
CDDP (mg)
1
80
145.0
22.3
8.7
41.8
80.0
2
72
114.3
13.7
6.9
37.9
75.6
3
56
107.8
15.4
6.5
40.8
76.4
4
24
91.7
11.7
5.5
40.0
80.0
5-6
6
100.0
11.2
6.0
40.0
80.0
Mean
240
111.8
14.9
6.7
40.1
78.4
Table 3 Response to TSCTV in evaluated patients
Stage
CR
PR
MR
NC
PD
Total
I
0
0
0
0
0
0
II
0
0
2
2
0
4
III
0
22
36
4
0
62
IV
0
0
3
4
3
19
Response
0
22
41
10
3
76
Percentage
(0%)
(28.9%)
(53.9%)
(13.1%)
(3.9%)
Table 4 Survival of 76 patients undergoing TSCTV
Stage
No of patients
No of survival (year)
0.5
1
2
3
I
0
0
0
0
0
II
4
4
4
3
2
III
62
62
60
32
19
IV
10
8
2
0
0
Total
76
74
66
35
21
Percentage
(97.4%)
(86.8%)
(46.1%)
(27.6%)
Table 5 Side effects and complication
Side effects and complications
Incidence No.(%)
Fever 38-39 °C
71 (88.7)
> 39 °C
18 (22.5)
Nausea and vomiting
60 (75.0)
Right hypochondrium pain
72 (90.0)
Cholecystitisa
5 (6.2)
Liver abscess
1 (1.2)
Hapatic failure
4 (5.0)
Ascites
6 (7.5)
Citation: Fan J, Ten GJ, He SC, Guo JH, Yang DP, Weng GY. Arterial chemoembolization for hepatocellular carcinoma. World J Gastroenterol 1998; 4(1): 33-37