Protective effects of autologous bone marrow-derived mesenchymal stem cell transplantation on acute radioactive enteritis in Beagle dogs

Table 1 Comparison of temperature and body weight among three groups with different doses of radiation

Time	Control (n = 6)		12 Gy (n = 6)		26 Gy (n = 6)
	T (°C)	W (kg)	T (°C)	W (kg)	T (°C)	W (kg)
Day 1	38.73 ± 0.54	11.86 ± 0.42	38.67 ± 0.47	12.10 ± 0.53	38.93 ± 0.6	11.80 ± 0.53
Day 3	38.73 ± 0.41	11.89 ± 0.42	39.30 ± 0.44	11.97 ± 0.59	41.63 ± 0.06a	10.23 ± 0.90a
Day 5	38.75 ± 0.57	11.91 ± 0.38	39.73 ± 0.12	11.40 ± 0.87	N	N
Day 7	38.70 ± 0.49	11.96 ± 0.39	40.23 ± 0.35a	10.47 ± 0.75a	N	N
Day 9	38.71 ± 0.39	12.03 ± 0.43	40.77 ± 0.25a	10.33 ± 0.51a	N	N
Day 11	38.76 ± 0.52	12.04 ± 0.41	40.30 ± 0.66a	10.73 ± 0.38a	N	N

^aP < 0.05.

T: Temperature; W: Weight; N: No data for the death of experimental animals.

Table 2 Histologic score before and after autologous bone marrow-derived mesenchymal stem cell transplantation

Group	Time	Mucosa damage	Inflammatory infiltration	Vascular congestion	Total score
Blank		0.0 ± 0.0	0.0 ± 0.0	0.0 ± 0.0	0.0 ± 0.0
Saline	Before transplantation	2.6 ± 0.5	2.6 ± 0.5	1.6 ± 0.5	6.8 ± 1.6
Saline	After transplantation	2.2 ± 0.4	1.8 ± 0.8	1.4 ± 0.5	5.2 ± 1.6
ABMSCs	Before transplantation	2.4 ± 0.5	2.8 ± 0.4	1.4 ± 0.5	6.6 ± 1.3
ABMSCs	After transplantation	1.6 ± 0.5	1.2 ± 0.4a	1.0 ± 0.0	3.8 ± 0.8a

^aP < 0.05, vs before autologous bone marrow-derived mesenchymal stem cell transplantation.

Relative scores of mucosa damage, inflammatory infiltration, and vascular congestion were set from 0 (absent) to 4 (maxim of each aspect, ++++) and the total score of each group was calculated. Histologic scores of different groups were recorded as the mean ± SD. ABMSCs: Autologous bone marrow-derived mesenchymal stem cells.