Mesalazine alleviated the symptoms of spontaneous colitis in interleukin-10 knockout mice by regulating the STAT3/NF-κB signaling pathway

Table 1 Disease activity index scale

	0	1	2
Ruffled fur	-	+	/
Occult fecal blood	-	+	/
Rectal prolapse	-	< 1 mm	> 1 mm
Stool consistency	-	Soft stool	Diarrhea

Table 2 Primer sequences (5’ to 3’)

Gene name	Forward primer	Reverse primer
STAT3	CTGGCTAGACAATATCATCGACC	GGCTTTGTGCTTAGGATGGC
NF-κB	GTGGAGGCATGTTCGGTAGTG	TCTTGGCACAATCTTTAGGGC
β-actin	GAGACCTTCAACACCCCAGC	TGCCTTACGGACCTCTTCTATC

STAT3: Signal transducer and activator of transcription 3; NF-κB: Nuclear factor kappa B.