Observational Study
Copyright ©The Author(s) 2024.
World J Gastroenterol. May 14, 2024; 30(18): 2454-2466
Published online May 14, 2024. doi: 10.3748/wjg.v30.i18.2454
Table 1 inical characteristics of 66 subjects
Clinical characteristic
DILI (n = 31)
HC (n = 35)
P value
Age, yr, median (IQR)50.0 (46.0-60.0)52.0 (45.0-61.0)0.585
Female19 (61.3)19 (54.3)0.566
Weight, kg, median (IQR)60.0 (53.0-74.0)63.0 (58.0-70.0)0.310
BMI, kg/m2, median (IQR)21.5 (20.2-25.0)22.9 (20.8-25.4)0.676
Laboratory examination
ALT, U/L, median (IQR)238.0 (91.0-526.0)22.0 (12.0-27.0)< 0.001
AST, U/L, median (IQR)182.0 (74.0-270.0)25.0 (16.0-30.0)< 0.001
TBIL, μmol/L, median (IQR)72.7 (32.1-117.4)8.5 (5.7-13.1)< 0.001
ALP, U/L, median (IQR)137.0 (92.0-215.0)86.0 (77.0-114.0)< 0.001
GGT, U/L, median (IQR)140.0 (82.0-213.0)32.0 (17.0-41.0)< 0.001
ALB, g/L, median (IQR)36.0 (32.0-39.0)41.0 (39.0-46.0)< 0.001
TBA, μmol/L, median (IQR)42.0 (11.0-73.0)9.0 (5.0-17.0)< 0.001
LDH, U/L, median (IQR)186.0 (158.0-202.0)188.0 (146.0-243.0)0.550
INR, median (IQR)1.0 (1.0-1.1)0.9 (0.9-1.0)< 0.001
BMI: Body mass index; ALT: Alanine transaminase; AST: Aspartate transaminase; GGT: γ-glutamyl transferase; TBIL: Total serum bilirubin; ALP: Alkaline phosphatase; GGT: Gamma-glutamyl transpeptidase; ALB: Aalbumin; TBA: Total bile acid; LDH: Lactate dehydrogenase; INR: International normalized ratio; DILI: Drug-induced liver injury; HC: Healthy control.