Effects of Linomide on growth and metastasis of implanted human gastric cancer in nude mice

Table 1 Inhibitory effect of Linomide in gastric cancer growth in nude mice

	n	Local tumor growth	Volume of local tumor (cm3)
Control	28	28/28 (100%)	1.36 ± 0.81
Linomide
80 mg/kg	10	10/10 (100%)	0.84 ± 0.51a
160 mg/kg	10	10/10 (100%)	0.62 ± 0.35b

^aP < 0.05,

^bP < 0.01, vs control group.

Table 2 Inhibitory effect of Linomide in hepatic metastasis

	n	Ratio of metastasis	Metastatic foci
Control	28	19/28 (67.9%)	4.2 ± 1.4
Linomide
80 mg/kg	10	4/10 (40.0%)a	2.5 ± 0.8
160 mg/kg	10	1/10 (10.0%)b	2

^aP < 0.05,

^bP < 0.01, vs control group.