Supply and quality of colonoscopy according to the characteristics of gastroenterologists in the French population-based colorectal-cancer screening program

Table 1 Evolution of the regional offer in number of gastroenterologists and the number of gastroenterologists having performed at least one colonoscopy, by year of performance of the screening colonoscopy

Year of colonoscopy	Nb of GE in IDF1		Number of gastroenterologists who performed a screening colonoscopy2
			Number of GE by seniority		Number of GE by density of GE in the municipality of practice of the GE			Number of GE by place of performance of the colonoscopy			Number of GE by annual number (A) of colonoscopies performed				Total (n) of GE in IDF (% GE ≥ 2 location)
	Nb of GE (density)3	Nb of municipalities with GE	Senior	New (% in n)	Low	Average	High	Private clinic	Private Hop.	Public Hop.	A = 1	A = 2-30	A = 30-100	A > 100
2010	761 (6.5)	155	627	-	134	85	493	415	114	214	119	473	35	-	627 (20.6)
2011	756 (6.4)	156	534	77 (12.6)	140	71	474	408	117	201	106	465	40	-	611 (17.2)
2012	759 (6.4)	155	538	57 (9.6)	116	79	473	383	112	206	117	454	24	-	595 (16.8)
2013	761 (6.4)	154	539	30 (5.3)	98	92	442	378	115	181	107	448	14	-	569 (16.5)
2014	757 (6.3)	155	522	63 (10.8)	129	75	451	384	106	193	123	448	14	-	585 (17.4)
2015	776 (6.4)	154	526	44 (7.7)	117	53	449	379	103	178	140	419	11	-	570 (13.9)
2016	784 (6.5)	154	629	98 (13.5)	128	65	628	432	143	312	97	447	175	8	727 (18.8)
2017	793 (6.5)	152	642	72 (10.1)	142	56	603	418	142	312	93	486	134	1	714 (19.9)
2018	799 (6.5)	149	665	64 (8.8)	141	51	626	424	151	312	100	488	139	2	729 (20.7)
2019	798 (6.5)	147	643	32 (4.7)	123	63	574	388	152	287	92	512	71	-	675 (21.8)
2020	802 (6.5)	142	619	76 (10.9)	147	50	582	412	162	265	124	475	96	-	695 (19.7)

¹Number of gastroenterologists (GE) registered in the region (source: National Council of the Order of Physicians).

²Number of gastroenterologists who performed a screening colonoscopy during the calendar year (regardless of the type of test and regardless of the date of the screening test).

³Density in Number of GE/100000 inhabitants: Regional average density (5.5 à 7.5 GE/100000 inhabitants) Low density of GE (< 5.5 GE/100000 habitants) and high density of GE (> 7.5 GE/100000 inhabitants).

GE: Gastroenterologist; Hop: Hospital; IDF: Ile-de-France; Nb: Number.

Table 2 Evolution of the number of colonoscopies performed according to the characteristics of the gastroenterologist, by year of performance of the screening colonoscopy, n (%)

Year of colonoscopy	Number of colonoscopies performed according to GE characteristics
	Number of colonoscopies by seniority of GE		Number of colonoscopies by density of GE in the municipality of practice of the GE1			Number of colonoscopies by place of performance of the colonoscopy			Number of colonoscopies by GE’s annual number (A) of colonoscopies performed				Total
	Senior	New	Low	Average	High	Clinic	Private Hop.	Public Hop.	A = 1	A = 2-30	A = 31-100	A > 100	Nb (n) of Colo performed in IDF (average Nb of Colo by GE)	Nb of Colo with place specified (% outside IDF)	Nb of Colo (% Place unspecified)
2010	6059	-	1535	900 (14.9)	3624 (59.8)	4507	830 (13.7)	722 (11.9)	119	4493 (74.2)	1447 (23.9)	-	6059 (11)	6161 (1.7)	6441 (4.4)
2011	6300	128 (2.0)	1684	712 (11.1)	4032 (62.7)	4677	946 (14.7)	805 (12.5)	106	4578 (71.2)	1744 (27.1)	-	6428 (12)	6543 (1.8)	6928 (5.6)
2012	5355	76 (1.4)	1186	766 (14.1)	3479 (64.1)	3818	830 (15.3)	783 (14.4)	117	4284 (78.9)	1030 (19.0)	-	5431 (11)	5533 (1.8)	5852 (5.5)
2013	4309	47 (1.1)	1045	737 (16.9)	2574 (59.1)	3156	660 (15.2)	540 (12.4)	107	3725 (85.5)	524 (12.0)	-	4356 (9)	4409 (1.2)	4712 (6.4)
2014	4320	132 (3.0)	1104	611 (13.7)	2737 (61.5)	3199	650 (14.6)	603 (13.5)	123	3718(83.5)	611 (13.7)	-	4452 (9)	4515 (1.4)	4746 (4.9)
2015	3712	63 (1.7)	879	446 (11.8)	2450 (64.9)	2692	604 (16.0)	479 (12.7)	140	3198 (84.7)	437 (11.6)	-	3775 (8)	3818 (1.1)	4034 (5.4)
2016	15196	333 (2.1)	3406	1862 (12.0)	10261 (66.1)	10886	2527 (16.3)	2116 (13.6)	97	5243 (33.8)	9148 (58.9)	1041	15529 (25)	15811 (1.8)	16651 (5.0)
2017	11519	192 (1.6)	2876	1262 (10.8)	7573 (64.7)	7919	1937 (16.5)	1855 (15.8)	93	5370 (45.9)	6137(52.4)	111	11711 (18)	11920 (1.8)	12345 (3.4)
2018	12181	164 (1.3)	2758	1190 (9.6)	8397 (68.0)	8233	2300 (18.6)	1812 (14.7)	100	5331 (43.2)	6684 (54.1)	230	12345 (19)	12602 (2.0)	13057 (3.5)
2019	8189	98 (1.2)	1582	932 (11.3)	5773 (69.7)	5365	1532 (18.5)	1390 (16.8)	92	5261 (63.5)	2934 (35.4)	-	8287 (13)	8487 (2.4)	8767 (3.2)
2020	9103	158 (1.7)	2088	755 (8.2)	6418 (69.3)	6654	1900 (20.5)	1199 (13.0)	124	5049 (54.5)	4088 (44.1)	-	9261 (15)	9501 (2.5)	9793 (3.0)

¹Density in Number of GE/100000 inhabitants: Regional average density (5.5 à 7.5 GE/100000 inhabitants), low density of GE (< 5.5 GE/100000 habitants) et High density of GE (> 7.5 GE/100000 inhabitants).

Colo: Screening colonoscopy; GE: Gastroenterologist; Hop.: Hospital; IDF: Ile-de-France; Nb: Number.

Table 3 Quality indicators and results of colonoscopies by period of performance of colonoscopy in people aged 50-74, residing in Ile-de-France, n (%)

Quality indicator	Period
	gFOBT	FIT	STOP-FIT	COVID	P value1
Total number (n) of colonoscopies	28679	46087	8767	9783
Existence of a GE consultation before colonoscopy
Nb (A) colonoscopies with date of consultation	5267 (18.4)	1517 (3.3)	406 (4.6)	198 (2.0)	< 10-3
Date of consultation ≠ Date of colonoscopy
Nb colonoscopies of which date of consultation ≠ colon date (% in A)	298.4 (56.7)	883 (58.2)	402 (99.0)	191 (96.5)	< 10-3
Time to colonoscopy
Average (in mean ± SD)	2.6 ± 2.9	3.0 ± 3.0	3.9 ± 3.9	3.5 ± 2.9	< 10-3*
Number of colonoscopies performed within one month	4957 (17.3)	4572 (9.9)	458 (5.2)	726 (7.4)	< 10-3
Number of colonoscopies performed beyond 7 mo	1520 (5.3)	2949 (6.4)	1034 (11.8)	933 (9.5)	< 10-3
Complete colonoscopy					< 10-3
Nb colonoscopies without information on performance	1263 (4.4)	2360 (5.1)	410 (4.7)	432 (4.4)
Number of complete colonoscopies	26530 (92.5)	41695(90.5)	8004 (91.3)	8981 (91.8)
Nb (B) of incomplete colonoscopies	886 (3.1)	2032 (4.4)	357 (4.1)	376 (3.8)
Reasons for incomplete colonoscopies					< 10-3
Unspecified: n (% in B)	206 (23.3)	617 (30.4)	109 (30.5)	114 (30.3)
Anatomical reason/Obstruction by lesion: n (% in B)	537 (60.6)	845 (41.6)	150 (42.0)	161 (42.8)
Insufficient preparation: n (% in B)	143 (16.1)	570 (28.1)	98 (27.5)	101 (26.9)
Redone incomplete colonoscopy
Number of redone colonoscopies (% B)	183 (20.7)	960 (47.2)	158 (44.3)	163 (43.3)	< 10-3
Frequency of incidents					0.14
No incidents reported: n	28873 (99.6)	45947 (99.7)	8740 (99.7)	9763 (99.8)
Related to anaesthesia/general condition: n	18 (0.06)	24 (0.05)	3 (0.03)	2 (0.02)
Related to endoscopy: n	88 (0.3)	116 (0.3)	22 (0.3)	18 (0.2)
Frequency of accidents					0.17
No accidents reported: n	28589 (99.7)	45970 (99.8)	8749 (99.8)	9763 (99.8)
Suspected complication: n	24 (0.08)	23 (0.05)	5 (0.04)	3 (0.03)
Exterior bleeding: n	57 (0.2)	66 (0.1)	14 (0.2)	12 (0.1)
Perforation: n	8 (0.03)	28 (0.06)	3 (0.03)	4 (0.04)
Deaths: n	1 (0.0)	0	0	0
Colonoscopies results
Detection rate: Nb of lesions	14857 (51.8)	29843 (64.8)	5565 (63.5)	5967 (60.1)	< 10-3
Nb Polyps (% HRP)	12947 (44.2)	26624 (56.4)	5040 (53.3)	5425 (51.8)	< 10-3
Nb of CRC (% CRC seen at colonoscopy)	1910 (61.4)	3219 (55.2)	525 (57.3)	542 (56.1)	< 10-3
% CRC with severity stage specified among Nb CRC2	90.3	80.5	74.3	72.3	< 10-3
Nb CRC with severity stage specified (% severe CRC) 2	1724 (50.7)	2592 (40.9)	390 (39.5)	392 (39.5)	< 10-3

¹Pearson’s χ²/Fisher’s exact test of proportion or Fisher’s F test (ANOVA).

²Any CRC ≥ T3 (subserous invaded) or ≥ N1 (at least one regional node invaded) or M1 (with metastasis) was considered severe colorectal cancer.

CRC: Colorectal cancer; FIT: Fecal immunochemical test; GE: Gastroenterologist; gFOBT: Guaiac fecal occult blood test; HRP: High risk polyps (advanced adenoma); Nb: Number.

Table 4 Average time (in months) to colonoscopy according to the characteristics of the cohort of gastroenterologists who performed at least one colonoscopy over each of the four periods (guaiac fecal occult blood test, fecal immunochemical test, STOP-fecal immunochemical test, and COVID)

Characteristics of the cohort of gastroenterologists	Nb of GE	Average time (in months) to colonoscopy, by period
		gFOBT		FIT		STOP-FIT		COVID		P1
		Nb of Colo	Average, 95%CI	Nb of Colo	Average, 95%CI	Nb of Colo	Average, 95%CI	Nb of Colo	Average, 95%CI
Overall	533	21509	2.6 [2.5; 2.6]	38352	3.0 [2.9; 3.0]	7342	3.9 [3.8; 4.0]	7995	3.5 [3.4; 3.6]	< 10-3
Annual Nb of Colo
1	2012	304	3.1 [2.8; 3.5]	150	3.3 [2.7; 3.8]	38	4.3 [3.1; 4.8]	51	4.0 [3.5; 4.6]	0.08
2-30	4812	16819	2.6 [2.5; 2.6]	15970	3.0 [3.0; 3.1]	4887	3.9 [3.8; 4.0]	4211	3.5 [3.4; 3.6]	< 10-3
31-100	442	4386	2.4 [2.3; 2.5]	21137	3.0 [2.9; 3.0]	2817	3.8 [3.6; 3.9]	3733	3.5 [3.4; 3.6]	< 10-3
> 100	0	0		1095	2.5 [2.3; 2.6]	0		0
Place of S-colo performance
Clinic	3552	15745	2.4 [2.4; 2.5]	27003	2.9 [2.8; 2.9]	5039	3.7 [3.6; 3.7]	5560	3.4 [3.3; 3.5]	< 10-3
Private hospital	1252	3041	2.5 [2.4; 2.6]	6500	2.9 [2.8; 3.0]	1359	3.6 [3.5; 3.7]	1621	3.4 [3.3; 3.5]	< 10-3
Public hospital	2352	2723	3.3 [3.2; 3.4]	4849	3.8 [3.7; 3.9]	940	5.1 [4.7; 5.9]	795	4.2 [3.8; 4.7]	< 10-3
Average density of GE (GE/100000iHbts)
Low	1272	4643	2.4 [2.3; 2.5]	8419	2.9 [2.8; 2.9]	1519	3.9 [3.8; 4.1]	1800	3.4 [3.3; 3.5]	< 10-3
Average	1082	3245	2.5 [2.4; 2.5]	4314	2.9 [2.8; 2.9]	810	4.1 [3.8; 4.4]	781	3.6 [3.4; 3.9]	< 10-3
High	4672	13621	2.6 [2.6; 2.7]	25619	3.0 [3.0; 3.1]	5009	3.8 [3.7; 3.9]	5395	3.5 [3.4; 3.6]	< 10-3
Annual Nb of Colo locations
1 location	4832	14437	2.6 [2.6; 2.7]	24851	3.0 [3.0; 3.1]	4763	3.8 [3.7; 3.9]	5160	3.5 [3.4; 3.6]	< 10-3
≥ 2 locations	1532	7072	2.4 [2.4; 2.5]	13501	2.9 [2.9; 3.0]	2575	4.0 [3.9; 4.1]	2816	3.5 [3.4; 3.7]	< 10-3
Residence of the patient
Colonoscopy’s supply municipality	3382	4947	2.5 [2.4; 2.5]	7775	2.9 [2.9; 3.0]	1502	3.9 [3.7; 4.1]	1530	3.5 [3.3; 3.6]	< 10-3
Other municipality in Colonoscopy’s supply department	4802	13259	2.5 [2.5; 2.6]	23754	3.0 [3.0; 3.1]	4401	3.9 [3.8; 4.0]	4982	3.5 [3.4; 3.6]	< 10-3
Other departments in IDF	4192	3303	2.7 [2.6; 2.8]	6823	2.9[2.9; 3.0]	1435	3.8 [3.6; 4.0]	1464	3.6 [3.5; 3.8]	< 10-3
Age (in yr) of the patients
50-54	4852	4995	2.7 [2.6; 2.8]	8018	3.1 [3.0; 3.2]	1695	4.1 [3.9; 4.2]	1616	3.8 [3.7; 4.0]	< 10-3
55-59	4522	4669	2.6 [2.5; 2.7]	7355	3.1 [3.0; 3.1]	1446	3.9 [3.7; 4.1]	1560	3.6 [3.4; 3.7]	< 10-3
60-64	4662	4889	2.5 [2.4; 2.6]	7851	3.0 [2.9; 3.0]	1478	3.7 [3.5; 3.9]	1531	3.5 [3.4; 3.7]	< 10-3
65-69	4642	3766	2.5 [2.4; 2.5]	8511	2.9 [2.8; 2.9]	1403	3.8 [3.6; 4.0]	1590	3.3 [3.1; 3.5]	< 10-3
≥ 70	4312	3190	2.4 [2.3; 2.5]	6617	2.9 [2.8; 3.0]	1316	3.7 [3.5; 3.8]	1679	3.4 [3.3; 3.6]	< 10-3

¹(Prob > F) ANOVA.

²This is the number of gastroenterologists (GEs) having performed a colonoscopy over the guaiac fecal occult blood test period, the same GE can be present in all of the modalities, for example the same GE having performed colonoscopies at 3 different sites corresponding to each of the density zones (low average high).

95%CI: 95% confidence interval; Colo: Screening colonoscopy; FIT: Fecal immunochemical test; GE: Gastroenterologist; gFOBT: Guaiac fecal occult blood test; iHbts: Inhabitants; IDF: Ile-De-France; Nb: Number.

Table 5 Proportion of colonoscopies performed beyond 7 mo and proportion of serious adverse events, according to the characteristics of the cohort of gastroenterologists who performed at least one colonoscopy in each of the three periods (guaiac fecal occult blood test, fecal immunochemical test, STOP-fecal immunochemical test, and COVID)

Characteristics of the cohort of gastroenterologists	Proportion of colonoscopies performed beyond 7 mo by period					Proportion of serious adverse events by period
	gFOBT	FIT	STOP-FIT	COVID	P1	gFOBT	FIT	STOP-FIT	COVID	P1
	Nb of Colo (% > 7 mo)	Nb of Colo (% > 7 mo)	Nb of Colo (% > 7mo)	Nb of Colo (% > 7 mo)		%EI	%EI		%EI
Overall	21509 (5.3)	38352 (6.2)	7342 (11.3)	7995 (9.2)	< 10-3	0.3	0.3	0.3	0.2	0.10
Annual Nb of Colo
1	304 (10.1)	150 (11.8)	38 (18.4)	51 (12.0)	< 10-3	0.3	0	0	0	0.67
2-30	16819 (5.5)	15970 (6.9)	4887 (11.8)	4211 (9.4)	< 10-3	0.3	0.4	0.3	0.1	0.09
31-100	4386 (4.1)	21137 (5.7)	2817 (10.6)	3733 (9.0)	< 10-3	0.4	0.2	0.3	0.2	0.25
> 100		1095 (3.7)					0.2
Place of Colo performance
Clinic	15745 (4.8)	27003 (5.4)	5039 (10.4)	5560 (8.3)	< 10-3	0.3	0.3	0.3	0.1	0.16
Private hospital	3041 (5.1)	6500 (5.9)	1359 (9.6)	1621 (9.5)	< 10-3	0.3	0.2	0.2	0.2	0.71
Public hospital	2723 (8.5)	4849 (10.6)	940 (18.8)	795 (15.1)	< 10-3	0.6	0.6	0.2	0.4	0.48
Average density of GE (GE/100000 iHbts)
Low	4643 (5.1)	8419 (5.8)	1519 (11.5)	1800 (9.1)	< 10-3	0.3	0.2	0.3	0.1	0.59
Average	3245 (4.9)	4314 (6.5)	810 (11.0)	781 (9.9)	< 10-3	0.2	0.3	0.1	0.5	0.48
High	13621 (5.5)	25619 (6.2)	5009 (11.3)	5395 (9.2)	< 10-3	0.4	0.3	0.3	0.1	0.04
Annual Nb of Colo locations
1 location	14437 (5.6)	24851 (6.3)	4763 (10.6)	5160 (9.5)	< 10-3	0.4	0.3	0.3	0.2	0.17
≥ 2 location	7072 (4.8)	13501 (6.0)	2575 (12.7)	2816 (8.7)	< 10-3	0.2	0.2	0.2	0.1	0.80
Residence of the patient
Colonoscopy’s supply municipality	4947 (4.9)	7775 (5.9)	1502 (11.6)	1530 (8.0)	< 10-3	0.2	0.3	0.3	0.0	0.18
Other municipality in Colonoscopy’s supply department	13259 (5.1)	23754 (6.0)	4401 (11.0)	4982 (9.6)	< 10-3	0.4	0.3	0.2	0.2	0.02
Other departments in IDF	3303 (6.6)	6823 (6.9)	1435 (12.1)	1464 (9.2)	< 10-3	0.3	0.4	0.4	0.3	0.80
Age (in yr) of the patients
50-54	4995 (6.7)	8018 (7.0)	1695 (12.2)	1616 (11.0)	< 10-3	0.2	0.2	0.1	0.1	0.43
55-59	4669 (5.7)	7355 (6.6)	1446 (11.8)	1560 (9.9)	< 10-3	0.3	0.3	0.4	0.2	0.79
60-64	4889 (4.7)	7851 (5.9)	1478 (10.3)	1531 (8.9)	< 10-3	0.4	0.3	0.5	0.3	0.76
65-69	3766 (4.4)	8511 (5.5)	1403 (11.7)	1590 (8.2)	< 10-3	0.4	0.3	0.3	0.1	0.20
≥ 70	3190 (4.6)	6617 (5.7)	1316 (10.6)	1679 (8.2)	< 10-3	0.5	0.4	0.2	0.2	0.49

¹Cochran Q test.

Colo: Screening colonoscopy; Colo+: Positive screening colonoscopy; FIT: Fecal immunochemical test; GE: Gastroenterologist; gFOBT: Guaiac fecal occult blood test; iHbts: Inhabitants; IDF: Ile-De-France; Nb: Number.

Table 6 Neoplasm detection rate at colonoscopy, according to the characteristics of the cohort of gastroenterologists who performed at least one colonoscopy in each of the three periods (guaiac fecal occult blood test, fecal immunochemical test, STOP-fecal immunochemical test, and COVID)

Characteristics of the cohort of gastroenterologists	Neoplasm detection rate at colonoscopy by period
	gFOBT	FIT-1	STOP-FIT	COVID	P1
	Nb of Colo (% Colo+)	Nb of Colo (% Colo+)	Nb of Colo (% Colo+)	Nb of Colo (% Colo+)
Overall	21509 (52.3)	38352 (65.0)	7342 (63.3)	7995 (60.1)	< 10-3
Annual Nb of Colo
1	304 (50.7)	150 (62.0)	38 (71.1)	51 (51.0)	0.02
2-30	16819 (53.6)	15970 (64.5)	4887 (63.7)	4211 (59.6)	< 10-3
31-100	4386 (47.6)	21137 (65.8)	2817 (62.5)	3733 (61.8)	< 10-3
> 100		1095 (58.6)	0	0
Place of S-colo performance
Clinic	15745 (52.4)	27 003 (64.9)	5039 (62.8)	5560 (60.1)	< 10-3
Private hospital	3041 (54.3)	6500 (65.0)	1359 (64.8)	1621 (62.7)	< 10-3
Public hospital	2723 (49.8)	4849 (65.6)	940 (63.7)	795 (59.5)	< 10-3
Average Density of GE (GE/100000iHbts)
Low	4643 (53.0)	8419 (64.5)	1519 (61.7)	1800 (58.4)	< 10-3
Average	3245 (53.1)	4314 (64.1)	810 (65.2)	781 (61.1)	< 10-3
High	13621 (51.9)	25619 (65.4)	5009 (63.4)	5395 (61.2)	< 10-3
Annual Nb of S-colo locations
1 location	14437 (52.8)	24851 (64.8)	4763 (63.0)	5160 (60.8)	< 10-3
≥ 2 locations	7072 (51.3)	13501 (65.6)	2575 (63.8)	2816 (60.2)	< 10-3
Residence of the patient
Colonoscopy’s supply municipality	4947 (53.4)	7775 (65.3)	1502 (61.1)	1530 (59.5)	< 10-3
Other municipality in Colonoscopy’s supply department	13259 (51.7)	23754 (65.0)	4401 (64.2)	4982 (61.2)	< 10-3
Other departments in IDF	3303 (53.1)	6823 (64.9)	1435 (62.8)	1464 (59.6)	< 10-3
Age (in yrs) of the patients
50-54	4995 (44.9)	8018 (56.5)	1695 (55.2)	1616 (52.9)	< 10-3
55-59	4669 (50.8)	7355 (63.1)	1446 (61.3)	1560 (58.9)	< 10-3
60-64	4889 (54.2)	7851 (67.9)	1478 (65.5)	1531 (63.1)	< 10-3
65-69	3766 (57.1)	8511 (68.9)	1403 (68.3)	1590 (65.3)	< 10-3
≥ 70	3190 (57.5)	6617 (69.2)	1316 (67.9)	1679 (62.8)	< 10-3

¹Cochran Q test.

Colo: Screening colonoscopy; Colo+: Positive screening colonoscopy; FIT: Fecal immunochemical test; GE: Gastroenterologist; gFOBT: Guaiac fecal occult blood test; iHbts: Inhabitants; IDF: Ile-De-France; Nb: Number.

Table 7 Multivariate analysis of the relationship between each dependent variable (binary variables 0/1: Screening colonoscopy performed beyond 7-mo; Serious adverse events, Yield of neoplasm at screening colonoscopy) and the predictive factors

Characteristics of the cohort of gastroenterologists	Colo performed beyond a 7-mo risk analysis		Serious adverse events risk analysis		Neoplasms risk analysis
	ORa, 95%CI	P1	ORa, 95%CI	P1	ORa, 95%CI	P1
Annual Nb of Colo (Ref: 1 Colo)
2-30	0.7 [0.6; 1.0]	0.002	2.5 [0.3; 18.2]	0.37	0.9 [0.7; 1.1]	0.41
> 30	0.7 [0.3; 0.9]	0.008	2.9 [0.9; 23.0]	0.05	0.8 [0.6; 1.1]	0.32
Place of S-colo performance (Ref: Clinic)
Private hospital	1.2 [0.9; 1.6]	0.18	0.7 [0.3; 1.8]	0.47	1.1 [0.9; 1.3]	0.41
Public hospital	2.1 [1.3; 3.6]	0.001	1.6 [0.3; 8.7]	0.60	1.1 [0.8; 1.4]	0.20
Density of GE (Ref: Low)
Average	0.9 [0.8; 1.0]	0.05	1.2 [0.6; 2.2]	0.59	1.0 [0.9; 1.1]	0.76
High	1.0 [1.0; 1.2]	0.28	1.2 [0.6; 2.3]	0.65	0.9 [0.8; 1.0]	0.04
Annual Nb of S-colo locations (Ref: 1 location)
≥ 2 locations	1.1 [0.8; 1.5]	0.11	1.6 [0.5; 4;4]	0.41	1.0 [0.8; 1.3]	0.84
Residence of the patient (Ref: Colonoscopy’s supply municipality)
Other municipality in Colonoscopy’s supply department	1.0 [0.9; 1.0]	0.30	1.0 [0.5; 2.1]	0.97	1.0 [0.9; 1.0]	0.31
Other departments in IDF	1.2 [1.1; 1.3]	< 10-3	1.2 [0.3; 5.2]	0.81	0.9 [0.8; 1.0]	0.13
Age (yrs) of the patients (Ref: 50-54 yr)
55-59	0.9 [0.8; 1.0]	0.03	1.6 [1.0; 2.6]	0.04	1.3 [1.2; 1.4]	< 10-3
60-64	0.8 [0.7; 0.9]	0.001	2.0 [1.2; 3.1]	0.006	1.6 [1.5; 1.6]	< 10-3
65-69	0.7 [0.7; 0.8]	< 10-3	1.9 [1.2; 3.0]	0.01	1.7 [1.6; 1.8]	< 10-3
≥ 70	0.7 [0.6; 0.8]	0.003	2.1 [1.3; 3.4]	0.002	1.7 [1.6; 1.8]	< 10-3
Period (Ref.: gFOBT)
FIT	1.2 [1.1; 1.2]	< 10-3	0.8 [0.4; 1.5]	0.11	1.6 [1.5; 1.7]	< 10-3
STOP-FIT	2.4 [2.1; 2.6]	< 10-3	0.8 [0.5; 1.3]	0.27	1.3 [1.1; 1.5]	< 10-3
COVID	2.0 [1.8; 2.2]	< 10-3	0.5 [0.3; 0.9]	0.02	1.1 [1.0; 1.3]	0.08

¹P > |z|.

95%CI: 95% confidence interval; Colo: Screening colonoscopy; FIT: Fecal immunochemical test; GE: Gastroenterologist; gFOBT: Guaiac fecal occult blood test; IDF: Ile-De-France; OR_a: Adjusted odds-ratio.