Clinical features, diagnosis, and treatment of Peutz-Jeghers syndrome: Experience with 566 Chinese cases

Table 1 General data of 566 patients with Peutz-Jeghers syndrome

General data	Classification	Cases	Percentage (%)
Gender	Male	313	55.3
	Female	253	44.7
Ethnic distribution	Han nationality	539	95.4
	Manchu	11	1.9
	Hui nationality	7	1.2
	Mongolian	4	0.7
	Tibetan	2	0.4
	Tujia nationality	1	0.2
	Zhuang nationality	1	0.2
	She minority	1	0.2
Family history of PJS	Yes	330	58.3
	No	236	41.7
ABO blood group	A	149	27.1
	B	175	31.8
	O	167	30.4
	AB	59	10.7
	Deletion	16	2.8
Rh blood group	Rh+	530	97.2
	Rh—	0	0
	Deletion	16	2.8
Marital history	Unmarried	330	58.3
	Married	236	41.7
Offspring inheritance	Yes	77	42.1
	No	106	57.9

PJS: Peutz-Jeghers syndrome.

Table 2 Clinical data of 566 patients with Peutz-Jeghers syndrome

Clinical data	Median	(P25, P75)	Extreme value
First treatment age	15	(9, 22)	0.5, 60
Follow-up age	26	(18, 34)	4, 65
Age of appearance of mucocutaneous pigmentation	2	(1, 4)	0, 33
Interval time between age of mucocutaneous pigmentation and occurrence of gastrointestinal symptoms	10	(5.5, 18)	0, 58
Gastric polyp burden	2	(1, 5)	1, 100
Maximum diameter of gastric polyps (mm)	8	(5, 15)	2, 80
Small intestinal polyp burden	3	(2, 8)	1, 100
Maximum diameter of small intestinal polyps (mm)	40	(25, 50)	1, 160
Colorectal polyps burden	2	(1, 5)	1, 100
Maximum diameter of colorectal polyps (mm)	30	(15, 45)	1, 120
Cumulative hospitalizations	2	(1, 3)	1, 11
Number of operations	1	(0, 2)	0, 7
Frequency of small intestinal enteroscopic examinations	2	(1, 3)	0, 12
Frequency of gastroenterographic examinations	1	(0, 2)	0, 16
Frequency of colonoscopic examinations	1	(0, 2)	0, 16