Effects of Granule Dendrobii on chronic atrophic gastritis induced by N-methyl-N'-nitro-N-nitrosoguanidine in rats

Table 1 Expression of proliferating cell nuclear antigen and B-cell lymphoma-2 in gastric tissues of different groups of rats

Grouping	PCNA						Bcl-2
	+++	++	+	-	n	P value	+++	++	+	-	n	P value
GD high	1	3	10	0	14	< 0.01	3	4	7	0	14	> 0.05
GD medium	5	4	3	0	12	> 0.05	2	8	2	0	12	> 0.05
GD low	3	2	7	0	12	< 0.01	1	6	5	0	12	> 0.05
YWS	4	3	5	0	12	< 0.05	2	7	3	0	12	> 0.05
Healthy animals	0	0	14	0	14	< 0.01	0	3	11	0	14	< 0.01
CAG no-treatment	9	5	0	0	14	-	5	7	2	0	14	-
6 groups of χ2-test	χ2 value	38.96					20.97
	P value	P < 0.01					P < 0.05

Data were evaluated for statistical significance by one-way ANOVA, least significant difference test and Dunnett T3 test. The P value in the table is the χ² test of each group compared to the group with chronic atrophic gastritis without treatment. The χ² value in the table is the χ² test of multi-group row lists with 6 groups. GD high: Chronic atrophic gastritis rats treated with a high dosage of Granule Dendrobii; GD medium: Chronic atrophic gastritis rats treated with a medium dosage of Granule Dendrobii; GD low: Chronic atrophic gastritis rats treated with low dosage of Granule Dendrobii; YWS: Chronic atrophic gastritis rats treated with Yangweishu; PCNA: Proliferating cell nuclear antigen; Bcl-2: B-cell lymphoma-2; CAG: Chronic atrophic gastritis.