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Copyright ©The Author(s) 2022.
World J Gastroenterol. Aug 28, 2022; 28(32): 4516-4526
Published online Aug 28, 2022. doi: 10.3748/wjg.v28.i32.4516
Table 1 Non-endoscopic methods for detection of Barrett’s esophagus
Device name
Application
Detection method
Company
FDA approved
Commercially available
Esophageal capsule endoscopy (ECE)SwallowedDirect visualization Given imagingYes (First generation: 2004)Three generations (SB1, SB2, SB3)
Tethered capsule endomicroscopy (OTC-TCE)SwallowedDirect visualization N/ANoNo
CytospongeSwallowed Cell collectionMedtronicYes (2018)Yes
EsophacapSwallowedCell collectionPAVmed (previously CapNostics)Yes (2021)No
EsoCheckSwallowedCell collectionPAVmed (Lucid Diagnostics)Yes (2019)Yes
Circulatory microRNAsBlood samplemiRNA collectionN/ANoNo
Volatile organic compounds (VOC)Breath sampleVOC collectionAeonose (Netherlands)NoNo