Mixed neuroendocrine-non-neuroendocrine neoplasms of the digestive system: A mini-review

doi:10.3748/wjg.v28.i19.2076

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May 21, 2022 (publication date) through May 6, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. May 21, 2022; 28(19): 2076-2087
Published online May 21, 2022. doi: 10.3748/wjg.v28.i19.2076

Table 1 Prognostic impact of neuroendocrine differentiation (summarized from Park et al[9])

Classification
Neuroendocrine differentiation (%)	0	< 10	10-30	30-70	> 70
Current classification	Non-NE	Non-NE	NNE-NED	MiNEN	NEC
5-yr overall survival	85	89	17¹	54	59

¹The 8 cases of non-NE tumors with NED in this study presented at a higher stage than the other tumors.

NE: Neuroendocrine; NED: Neuroendocrine differentiation; NNE: Non-neuroendocrine; MiNEN: Mixed neuroendocrine-non-neuroendocrine neoplasm; NEC: Neuroendocrine carcinoma.

Citation: Toor D, Loree JM, Gao ZH, Wang G, Zhou C. Mixed neuroendocrine-non-neuroendocrine neoplasms of the digestive system: A mini-review. World J Gastroenterol 2022; 28(19): 2076-2087
URL: https://www.wjgnet.com/1007-9327/full/v28/i19/2076.htm
DOI: https://dx.doi.org/10.3748/wjg.v28.i19.2076