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©The Author(s) 2021.
World J Gastroenterol. Mar 7, 2021; 27(9): 854-865
Published online Mar 7, 2021. doi: 10.3748/wjg.v27.i9.854
Published online Mar 7, 2021. doi: 10.3748/wjg.v27.i9.854
Table 1 Comparison of clinical and pathologic variables of study patients
Variables | CR group | PG group | P value |
Age, median (range), in yr | 58 (32-73) | 61 (28-75) | 0.532 |
Sex | 0.168 | ||
Male | 8 | 16 | |
Female | 10 | 9 | |
Size in cm | 0.549 | ||
≤ 2 | 1 | 0 | |
2.1-5.0 | 6 | 6 | |
5.1-10 | 7 | 13 | |
> 10 | 4 | 6 | |
Histologic type | 0.71 | ||
Spindle | 13 | 18 | |
Epitheloid | 1 | 3 | |
Mixed | 4 | 4 | |
Mitotic index, per 50 HPF | 0.766 | ||
≤ 5 | 13 | 17 | |
> 5 | 5 | 8 | |
Ki-67 | 0.163 | ||
≤ 5% | 15 | 16 | |
> 5% | 3 | 9 | |
CD117 | 0.929 | ||
Positive | 16 | 22 | |
Negative | 2 | 3 | |
CD34 | 0.159 | ||
Positive | 15 | 24 | |
Negative | 3 | 1 | |
DOG-1 | 0.083 | ||
Positive | 13 | 23 | |
Negative | 5 | 2 | |
NIH risk category | 0.476 | ||
Very low risk | 1 | 0 | |
Low risk | 5 | 4 | |
Intermediate risk | 7 | 12 | |
High risk | 5 | 9 | |
Length of the upper edge of the GIST crossing the Z-line, mean ± SD (cm) | 0.639 (0.29) | 1.024 (0.395) | 0.193 |
Circumference of the EGJ involvement | 0.716 | ||
T ≤ 1/4 | 10 | 13 | |
1/4 < T ≤ 2/4 | 7 | 8 | |
2/4 < T ≤ 3/4 | 1 | 3 | |
T > 3/4 | 0 | 1 | |
Heartburn, postoperative | |||
Yes | 3 | 16 | 0.004 |
No | 15 | 9 | |
Oral antacids, postoperative | |||
Yes | 4 | 18 | 0.002 |
No | 14 | 7 |
Table 2 Comparison of intra-operative and postoperative variables between two surgical procedures for type A esophagogastric junction-gastrointestinal stromal tumors
CR group, n = 18 | PG group, n = 25 | P value | 95%CI | ||
Lower | Upper | ||||
Operating time in min | 108.61 ± 30.13 | 137.80 ± 51.04 | 0.029 | -56.41 | -0.97 |
Intraoperative blood loss in mL | 59.44 ± 23.08 | 90.60 ± 35.62 | 0.069 | -53.53 | -11.78 |
First passage of flatus time in h | 29.11 ± 15.35 | 74.24 ± 40.39 | 0.013 | -65.389 | -24.87 |
Days to oral intake | 3.56 ± 1.65 | 8.68 ± 3.88 | 0.006 | -7.09 | -3.16 |
Postoperative hospital stay in d | 6.00 ± 2.40 | 10.96 ± 4.15 | 0.049 | -7.17 | -2.75 |
Negative margin, % | 100 | 100 |
Table 3 Postoperative esophageal 24-h pH parameters of patients who underwent surgery for type A esophagogastric junction-gastrointestinal stromal tumors
Mean 24-h pH | Total time for pH < 4 (min) | Acid reflux number of 24 h | Regurgitation events, > 5 min | ||
Standing | Lying | ||||
CR group, n = 18 | 4.97 ± 1.44 | 31.83 ± 22.65 | 17.83 ± 11.25 | 35.62 ± 15.71 | 1.44 ± 1.68 |
PG group, n = 25 | 3.41 ± 1.15 | 184.48 ± 118.74 | 32.68 ± 15.89 | 58.81 ± 19.13 | 6.04 ± 1.92 |
P value | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 |
Table 4 Postoperative health-related quality of life of study patients
PF | RP | BP | GH | VT | SF | RE | MH | |
CR group, n = 18 | 53.72 ± 2.13 | 54.61 ± 1.61 | 60.94 ± 1.86 | 61.56 ± 1.75 | 61.72 ± 3.49 | 55.11 ± 2.24 | 50.61 ± 2.93 | 55.00 ± 2.27 |
PG group, n = 25 | 48.00 ± 3.64 | 48.36 ± 2.89 | 49.80 ± 4.12 | 50.72 ± 5.15 | 52.20 ± 4.06 | 44.60 ± 2.63 | 37.16 ± 4.08 | 46.12 ± 3.95 |
P value | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 |
- Citation: Zheng GL, Zhang B, Wang Y, Liu Y, Zhu HT, Zhao Y, Zheng ZC. Surgical resection of esophagogastric junction stromal tumor: How to protect the cardiac function. World J Gastroenterol 2021; 27(9): 854-865
- URL: https://www.wjgnet.com/1007-9327/full/v27/i9/854.htm
- DOI: https://dx.doi.org/10.3748/wjg.v27.i9.854