Copyright
©The Author(s) 2021.
World J Gastroenterol. Oct 7, 2021; 27(37): 6161-6179
Published online Oct 7, 2021. doi: 10.3748/wjg.v27.i37.6161
Published online Oct 7, 2021. doi: 10.3748/wjg.v27.i37.6161
Table 1 Representative studies presenting gut microbial dysbiosis in alcoholic fatty liver disease
| Ref. | Sequencing method | Overgrown microbes | Depleted microbes | Model |
| Yan et al[63] (2011) | Pyrosequencing | ↑Bacteroidales | ↓Lactococcus | Murine |
| ↑Bacteroides | ↓Pediococcus | |||
| ↑Porphyromonadaceae | ↓Lactobacillus | |||
| ↓Leuconostoc | ||||
| Otterson et al[64] (2013) | Pyrosequencing | ↑Corynebacterium | ↓Bacteroides | Murine |
| ↑Alcaligenes | ↓Tannerella | |||
| ↑Listeria | ↓unclassified Lachnospiraceae | |||
| ↑Acetivibrio | ↓undefined Ruminococcaceae | |||
| ↑Allobaculum | ||||
| Lowe et al[71] (2017) | 16S rDNA | ↑Actinobacteria | ↓Tenericutes | Murine |
| ↑Eubacteriaceae | ↓Verrucomicrobia | |||
| ↓Lachnospiraceae | ||||
| ↓Moraxellaceae | ||||
| ↓Akkermansia | ||||
| Grander et al[73] (2018) | Illumina MiSeq | ↑Olsenella | ↓Acinetobacter | Murine |
| ↑Eubacterium | ↓Anaerotruncus | |||
| ↑Acetivibrio | ↓Akkermansia | |||
| ↓Blautia | ||||
| Kakiyama et al[74] (2013) | Pyrosequencing | ↑Enterobacteriaceae | ↓Blautia | Human |
| ↑Veillonellaceae | ↓Ruminococcaceae | |||
| ↓Lachnospiraceae | ||||
| ↓Rikenellaceae | ||||
| Bajaj et al[75] (2014) | Pyrosequencing | ↑Enterococcaeae | ↓Clostridiales XIV | Human |
| ↑Staphylococcaceae | ↓Ruminococcaceae | |||
| ↑Enterobacteriaceae | ↓Lachnospiraceae | |||
| Yang et al[83] (2017) | Illumina MiSeq | ↑Candida spp. | ↓Epicoccum | Human |
| ↑Candida albicans | ↓Unclassified fungi | |||
| ↑Candida dubliniensis | ↓Galactomyces | |||
| ↓Debaryomyces | ||||
| Ferrere et al[144] (2017) | Illumina MiSeq | ↑Actinobacteria | ↓Bacteroidetes | Murine |
| ↑Firmicutes | ↓Proteobacteria | |||
| ↑Coriobacteriaceae | ||||
| ↑Odoribacteriacea | ||||
| ↑Clostridiaceae | ||||
| ↑Dorea | ||||
| Wang et al[145] (2019) | Illumina MiSeq | ↑Verrucomicrobia | ↓Bacteroidetes | Monkey |
| ↑Proteobacteria | ↓Cytophagales | |||
| ↑Optitutus | ↓Flavobacteriales | |||
| ↑Botrytis | ↓Sphingobacteriales | |||
| ↑Sporothrix | ↓Lactobacillales | |||
| ↓Nitrosomonadales | ||||
| ↓Opitutales | ||||
| ↓Helotiales | ||||
| ↓Ophiostomatales | ||||
| Zhong et al[146] (2021) | Illumina MiSeq | ↑Proteobacteria | ↓Ruminococcaceae | Human |
| ↑Fusobacteria | ↓Faecalibacterium | |||
| ↑Fusobacteriaceae | ↓Lachnospira | |||
| ↑Enterobacteriaceae | ↓Agathobacter | |||
| ↑Burkholderiaceae | ↓Ruminococcus | |||
| ↑Fusobacterium | ||||
| ↑Escherichia-Shigella |
Table 2 Representative studies presenting gut microbial dysbiosis in non-alcoholic fatty liver disease
| Ref. | Sequencing method | Overgrown microbes | Depleted microbes | Model |
| Michail et al[97] (2015) | Ion torrent | ↑Actinobacteria | ↓Erysipelotrichia | Human |
| ↑Prevotella | ↓Alphaproteobacteria | |||
| ↑Clostridia | ↓Verrucomicrobia | |||
| ↑Fusobacteria | ||||
| ↑Epsilonproteobacteria | ||||
| ↑Gammaproteobacteria | ||||
| Wang et al[91] (2016) | Pyrosequencing | ↑Bacteroidaceae | ↓Lachnospiraceae | Human |
| ↑Prevotellaceae | ↓Ruminococcaceae | |||
| ↓Lactobacillaceae | ||||
| Raman et al[95] (2013) | Pyrosequencing | ↑Alphaproteobacteria | ↓Ruminococcaceae | Human |
| ↑Lactobacillaceae | ↓Oscillibacter | |||
| ↑Lachnospiraceae | ↓Porphyromonadaceae | |||
| ↑Veillonellaceae | ||||
| Chierico et al[94] (2017) | Pyrosequencing | ↑Actinobacteria | ↓Bacteroidetes | Human |
| ↑Bradyrhizobium | ↓Oscillospira | |||
| ↑Anaerococcus | ↓Rikenellaceae | |||
| ↑Peptoniphilus | ||||
| ↑Propionibacterium acnes | ||||
| ↑Dorea | ||||
| ↑Ruminococcus | ||||
| Hoyles et al[90] (2018) | Shotgun | ↑Proteobacteria | ↓Firmicutes | Human |
| ↑Actinobacteria | ↓Euryarchaeota | |||
| ↑Verrucomicrobia | ||||
| Shen et al[92] (2017) | 16S rDNA | ↑Proteobacteria | ↓Bacteroidetes | Human |
| ↑Fusobacteria | ↓Prevotellaceae | |||
| ↑Lachnospiraceae | ↓Ruminococcaceae | |||
| ↑Enterobacteriaceae | ↓Prevotella | |||
| ↑Erysipelotrichaceae | ||||
| ↑Streptococcaceae | ||||
| ↑Escherichia Shigella | ||||
| Zhu et al[84] (2013) | Pyrosequencing | ↑Bacteroidetes | ↓Actinobacteria | Human |
| ↑Proteobacteria | ↓Bifidobacteriaceae | |||
| ↑Alcaligenaceae | ↓Clostridiales family XI | |||
| ↑Campylobacteraceae | ↓Lachnospiraceae | |||
| ↑Enterobacteriaceae | ||||
| Chierico et al[94] (2017) | Pyrosequencing | ↑Coriobacteriaceae | ↓Porphyromonadaceae | Human |
| ↑Bacteroidaceae | ↓Rikenellaceae | |||
| Minicis et al[147] (2014) | Pyrosequencing | ↑Firmicutes | ↓Bacteroidetes | Murine |
| ↑Actinobacteria | ||||
| Lee et al[148] (2020) | 16S rDNA | ↑Firmicutes | ↓Bacteroidetes | Murine |
| ↑Deferribacters | ↓Lactobacillus murinus | |||
| ↑Helicobacter japonicus | ||||
| ↑Mucispirillum schaedleri | ||||
| ↑Flintibacter butyricus |
- Citation: Sharma SP, Suk KT, Kim DJ. Significance of gut microbiota in alcoholic and non-alcoholic fatty liver diseases. World J Gastroenterol 2021; 27(37): 6161-6179
- URL: https://www.wjgnet.com/1007-9327/full/v27/i37/6161.htm
- DOI: https://dx.doi.org/10.3748/wjg.v27.i37.6161