Copyright ©The Author(s) 2021.
World J Gastroenterol. Jul 28, 2021; 27(28): 4582-4602
Published online Jul 28, 2021. doi: 10.3748/wjg.v27.i28.4582
Table 1 List of oncogenic and tumor suppressor microRNAs in pancreatic cancer cells under hypoxia
Oncogenic activity
miR-519Anti-tumorInhibits cell growth and invasiveness[138]
miR-58anAnti-tumorReduces tumorigenesis[139]
miR-454Anti-tumorDecreases cell proliferation[140]
miR-210Pro-tumorRegulates cell cycle and promotes angiogenesis[142]
miR-191Pro-tumorPromotes tumor growth, invasion, and metastasis[143]
miR-212Pro-tumorPromotes tumor growth, vessel invasion, and metastasis[144]
miR-21Pro-tumorInduces cell proliferation, invasion, and metastasis[119,145]
miR-210Pro-tumorIncreases migration, invasion, and angiogenesis[119]
miR-646Pro-tumorPromotes proliferation and invasion[147]
miR-125aPro-tumorIncreases tumor cell viability[148]
miR-96-5pAnti-tumorInhibits angiogenesis[132]
miR-153Anti-tumorAvoids immune escape of tumor cells from natural killer cells[146]