Spontaneous regression of gastric gastrinoma after resection of metastases to the lesser omentum: A case report and review of literature

Table 1 Case reports of gastric gastrinoma

Case	Ref.	Year	Age	Gender	Symptoms	Symptom duration (yr)	History of peptic ulcer	Location	Size (mm)	Metastases	Gastrin before surgery (pg/mL)	Gastrin after surgery (pg/mL)	Treatment	Follow-up (mo)	Recurrence
1	Royston et al[16]	1972	65	M	Abdominal pain	14	+	Whole stomach	Large	-	> 1000	Undetectable	Total gastrectomy	15	-
2	Larsson et al[17]	1973	65	M	Abdominal pain, hematemesis	10	+	Antro-pylorus	10	-	NA	NA	Gastrectomy	12	-
3	Bhagavan et al[18]	1974	11	M	Acute peritonitis	0	-	Antrum (multiple)	Micro-scopic	-	> 1000	11000	Total gastrectomy	12	NA
4	Russo et al[19]	1980	51	F	Dyspepsia	7	-	Antrum-body junction	10	-	265	< 100	Polypectomy, antrectomy + splenectomy	36	-
5	Thompson et al[20]	1985	19	M	NA	3	+	Antrum	20	Liver	3000-4000	Normal	Total gastrectomy + segmental hepatectomy	NA	-
6	Liu et al[21]	1989	50	M	Pain, diarrhea, vomiting, weight loss	1.5	+	Antrum	< 10	Lymph node	1100-3000	153	Total gastrectomy	36	+
7	Liu et al[21]	1989	36	F	Pain, diarrhea, vomiting, weight loss	3.5	+	Lower body/antrum-body junction (multiple)	60	Lymph node, liver	518	4900	Subtotal gastrectomy	29 (dead)	NA
8	Werbel et al[22]	1989	72	M	Nausea, vomiting, anorexia, weight loss	8	+	Antrum	15	-	340	40	Antrectomy + vagotomy	12	-
9	Rindi et al[5]	1993	NA	NA	NA	NA	+	Pylorus	20	-	Elevated	Normal	Distal gastrectomy	NA	-
10	Wu et al[4]	1997	40	M	NA	NA	NA	Pylorus	NA	-	373	250	Enucleation	140	+
11	de Leval et al[23]	2002	91	M	Nausea, vomiting, anorexia, weight loss	4	+	Antrum	55	Lymph node, liver	3500	NA	None	0 (dead)	NA
12	Tartaglia et al[15]	2005	37	M	Abdominal pain, nausea	8	+	Angulus	7	Hepatogastric ligament	420	95	Endoscopic resection, subtotal gastrectomy + left hepatic lobectomy, lanreotide	72	+
13	Our case	2020	37	M	Abdominal pain	9	+	Antrum	7	Lesser omentum	41100	167	Tumor resection	30	-

Table 2 Case reports of primary gastrinoma of the lesser omentum

Case	Ref.	Year	Age	Gender	Symptoms	Size (mm)	Gastrin before surgery (pg/mL)	Gastrin after surgery (pg/mL)	Treatment	Follow-up (mo)	Recurrence
1	Wolfe et al[41]	1982	51	M	Recurrent duodenal ulcer	NA	753	112	Total gastrectomy	60	-
2	Wolfe et al[41]	1982	15	M	Hematemesis, abdominal pain, diarrhea	25	455	41	Tumor resection	12	-
3	Kohyama et al[42]	2007	74	F	Abdominal pain	40	1850	118	Resection of remnant stomach with tumor	24	-
4	Chang et al[43]	2010	13	M	Abdominal pain, diarrhea	45 × 37	1263	Normal	Tumor resection	36	-
5	Labidi et al[44]	2018	26	M	Melena, abdominal pain	50 × 40	306	Normal	Tumor resection	6	-