MiR-19a-3p regulates the Forkhead box F2-mediated Wnt/β-catenin signaling pathway and affects the biological functions of colorectal cancer cells

Table 1 Correlation of miR-19a-3p and Forkhead box F2 with pathological data of colorectal cancer patients

Factors	n	Relative expression of miR-19a-3p	t	P value	Relative expression of FOXF2	t	P value
Sex
	Male (n = 32)	1.08 ± 0.14	9.600	< 0.001	0.41 ± 0.13	9.686	< 0.001
	Female (n = 30)	1.41 ± 0.13			0.73 ± 0.13
Age
	< 57 years-old (n = 24)	1.03 ± 0.13	9.140	< 0.001	0.36 ± 0.11	10.080	< 0.001
	≥ 57 years-old (n = 38)	1.37 ± 0.15			0.70 ± 0.14
TNM stage
	I, II (n = 35)	1.1 ± 0.14	9.203	< 0.001	0.43 ± 0.13	9.910	< 0.001
	III, IV (n = 27)	1.42 ± 0.13			0.76 ± 0.13
Tumor size
	< 3 cm (n = 30)	1.06 ± 0.13	10.290	< 0.001	0.4 ± 0.12	10.370	< 0.001
	≥ 3 cm (n = 32)	1.4 ± 0.13			0.73 ± 0.13
Lymph node metastasis
	Yes (n = 42)	1.12 ± 0.14	10.780	< 0.001	0.46 ± 0.14	9.615	< 0.001
	No (n = 20)	1.49 ± 0.09			0.81 ± 0.12
Differentiation
	Low (n = 27)	1.39 ± 0.14	10.290	< 0.001	0.38 ± 0.12	10.080	< 0.001
	Medium and high (n = 35)	1.05 ± 0.12			0.72 ± 0.14

TNM: Tumor-node-metastasis; FOXF2: Forkhead box F2.