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©The Author(s) 2020.
World J Gastroenterol. Mar 28, 2020; 26(12): 1352-1364
Published online Mar 28, 2020. doi: 10.3748/wjg.v26.i12.1352
Published online Mar 28, 2020. doi: 10.3748/wjg.v26.i12.1352
Table 1 Characteristics of the study population
Variable | Value |
Recipient variables (n = 544) | |
Age (mo) | 8.20 (7.00-13.95) |
Weight (kg) | 7.70 (6.80-9.20) |
Male (%) | 257 (47.24) |
PELD score | 17.00 (10.00-21.00) |
Previous KP | 216 (39.85%) |
Donor variables (n = 544) | |
Donor age (yr) | 31.00 (27.00-36.00) |
Donor liver weight (g) | 255.00 (225.00-290.00) |
Donor liver cold ischemia time (min) | 65.50 (56.00-77.00) |
Table 2 Independent predictive factors of in-hospital patient survival
Independent predictive factor | Hospital death | P value | |
Yes | No | ||
Age (mo) | |||
≤ 36 | 35 | 440 | 0.847 |
> 36 | 4 | 64 | |
Gender | |||
Male | 19 | 238 | 0.857 |
Female | 20 | 266 | |
Weight (kg) | |||
≤ 10 | 33 | 386 | 0.266 |
> 10 | 6 | 116 | |
Diagnosis | |||
Cholestatic cirrhosis | 38 | 449 | 0.247 |
Metabolic disease | 1 | 44 | |
Others | 0 | 11 | |
Previous KP | |||
No | 25 | 301 | 0.611 |
Yes | 14 | 201 | |
PELD score | |||
≤ 2 | 36 | 372 | 0.0321 |
> 2 | 3 | 118 | |
Preoperative Hb (g/dL) | |||
≤ 8 | 15 | 121 | 0.058 |
> 8 | 24 | 369 | |
Anesthesia duration (min) | |||
≤ 600 | 26 | 408 | 0.0271 |
> 600 | 13 | 94 | |
Operation duration (min) | |||
≤ 480 | 22 | 388 | 0.0031 |
> 480 | 17 | 114 | |
Anhepatic phase (min) | |||
≤ 40 | 22 | 227 | 0.145 |
> 40 | 16 | 270 | |
Intraoperative blood loss (mL) | |||
≤ 200 | 23 | 375 | 0.0451 |
> 200 | 15 | 123 | |
GRWR (%) | |||
2 ≤ x ≤ 4 | 28 | 348 | 0.593 |
< 2 or > 4 | 8 | 124 | |
Cold ischemia time (min) | |||
≤ 60 | 17 | 178 | 0.241 |
> 60 | 18 | 284 | |
Perioperative RBC transfusion (U) | |||
≤ 1 | 22 | 320 | 0.369 |
> 1 | 17 | 183 | |
Perioperative blood transfusion (U) | |||
Yes | 39 | 466 | 0.099 |
No | 0 | 38 | |
Postoperative length of stay (d) | |||
≤ 30 | 27 | 337 | 0.278 |
> 30 | 8 | 156 | |
ICU MV duration (h) | |||
≤ 24 | 20 | 370 | 0.199 |
> 24 | 6 | 60 | |
ICU length of stay (d) | |||
≤ 9 | 13 | 342 | 0.0001 |
> 9 | 15 | 95 |
Table 3 Multivariate analysis of one-year patient survival
Independent predictive factor | HR | 95%CI | P value |
ICU length of stay (d) | |||
≤ 9 | 1 | ||
> 9 | 2.101 | 1.104-3.999 | 0.024 |
ICU MV duration (h) | |||
≤ 8 | 1 | ||
> 8 | 2.230 | 1.159-4.290 | 0.016 |
PELD score | |||
≤ 2 | 1 | ||
> 2 | 3.729 | 1.133-12.274 | 0.030 |
Preoperative Hb (g/dL) | |||
≤ 8 | 1 | ||
> 8 | 0.637 | 0.327-1.239 | 0.184 |
Table 4 Multivariate analysis of 3-year patient survival
Independent predictive factor | HR | 95%CI | P value |
ICU length of stay (d) | |||
≤ 9 | 1 | ||
> 9 | 1.966 | 1.122-3.446 | 0.018 |
Length of surgery (h) | |||
≤ 8 | 1 | ||
> 8 | 1.904 | 1.066-3.402 | 0.030 |
PELD | |||
≤ 2 | 1 | ||
> 2 | 3.659 | 1.303-10.274 | 0.014 |
- Citation: Pan ZY, Fan YC, Wang XQ, Chen LK, Zou QQ, Zhou T, Qiu BJ, Lu YF, Shen CH, Yu WF, Luo Y, Su DS. Pediatric living donor liver transplantation decade progress in Shanghai: Characteristics and risks factors of mortality. World J Gastroenterol 2020; 26(12): 1352-1364
- URL: https://www.wjgnet.com/1007-9327/full/v26/i12/1352.htm
- DOI: https://dx.doi.org/10.3748/wjg.v26.i12.1352