Copyright
©The Author(s) 2019.
World J Gastroenterol. Feb 7, 2019; 25(5): 622-631
Published online Feb 7, 2019. doi: 10.3748/wjg.v25.i5.622
Published online Feb 7, 2019. doi: 10.3748/wjg.v25.i5.622
Table 1 Parameters of diffusion-weighted imaging, T1-weighted imaging, T2-weighted imaging, and VIBE sequence
Parameter | DWI | In/out of phase | T2-weighted imaging | VIBE |
T1-weighted imaging | ||||
Repetition time (ms) | 5600 | 81 | 2160 | 3.95 |
Echo time (ms) | 68 | 1.4 | 100 | 1.92 |
Field of view (mm2) | 380 × 289 | 400 × 325 | 433 × 433 | 400 × 296 |
Scan matrix | 100 × 76 | 352 × 286 | 320 × 20288 | 352 × 256 |
Slice thickness (mm) | 6 | 6 | 6 | 2 |
Slice gap (mm) | 1 | 2.7 | 2.7 | 0 |
Number of excitation | … | 1 | 2 | 1 |
Table 2 Patients’ baseline characteristics
Characteristic | Value |
Clinical information | |
Age (yr) | 50.31 ± 10.87 (range: 26-77) |
Male/female | 157/46 |
Etiology of liver disease | |
Hepatitis B virus | 194 (95.57%) |
Hepatitis C virus | 8 (3.94%) |
Both hepatitis B and C virus | 1 (0.49%) |
Tumor size (cm) | Median 5.3 (range: 1.1-12.8) |
AFP level (ng/mL) | 102.3 ng/mL (range 1.2-15926.0) |
Serum AST (≥ 35 IU/L) | 107 (52.7%) |
Serum ALT (≥ 40 IU/L) | 82 (40.4%) |
Table 3 Sensitivity, specificity, and accuracy of the liver imaging reporting and data system category for diagnosing hepatocellular carcinoma with gadoxetic-acid enhanced magnetic resonance imaging
Group | DWI | Sensitivity (100%) | Specificity (100%) | Accuracy (100%) | PPV (100%) | NPV (100%) | Youden index |
LR-5 | A-DWI | 61.2 (101/165) | 92.5 (74/80) | 71.4 (175/245) | 94.4 (101/107) | 53.6 (74/138) | 0.537 |
P-DWI | 61.2 (101/165) | 92.5 (74/80) | 71.4 (175/245) | 94.4 (101/107) | 53.6 (74/138) | 0.537 | |
LR-4/5 | A-DWI | 73.9 (122/165) | 80 (64/80) | 75.9 (186/245) | 88.4(122/138) | 59.8 (64/107) | 0.539 |
P-DWI | 87.9 (145/165) | 80 (64/80) | 85.3 (209/245) | 90.1 (145/161) | 76.2 (64/84) | 0.679 | |
LR-4/5/M | A-DWI | 75.8 (125/165) | 58.8 (47/80) | 70.2 (172/245) | 79.1 (125/158) | 54 (47/87) | 0.346 |
P-DWI | 87.9 (145/165) | 58.8 (47/80) | 78.4 (192/245) | 81.5 (145/178) | 70.1 (47/67) | 0.467 | |
LR-4/5/TIV | A-DWI | 75.8 (125/165) | 75 (60/80) | 75.5 (185/245) | 86.2 (125/145) | 60 (60/100) | 0.508 |
P-DWI | 89.7 (148/165) | 75 (60/80) | 84.9 (208/245) | 88.1 (148/168) | 77.9 (60/77) | 0.647 |
- Citation: Zhang T, Huang ZX, Wei Y, Jiang HY, Chen J, Liu XJ, Cao LK, Duan T, He XP, Xia CC, Song B. Hepatocellular carcinoma: Can LI-RADS v2017 with gadoxetic-acid enhancement magnetic resonance and diffusion-weighted imaging improve diagnostic accuracy? World J Gastroenterol 2019; 25(5): 622-631
- URL: https://www.wjgnet.com/1007-9327/full/v25/i5/622.htm
- DOI: https://dx.doi.org/10.3748/wjg.v25.i5.622