Hwang YJ, Park SM, Ahn S, Lee JC, Park YS, Kim N. Accuracy of an administrative database for pancreatic cancer by international classification of disease 10th codes: A retrospective large-cohort study. World J Gastroenterol 2019; 25(37): 5619-5629 [PMID: 31602162 DOI: 10.3748/wjg.v25.i37.5619]
Corresponding Author of This Article
Nayoung Kim, MD, PhD, Professor, Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 82 Gumi-ro 173 Beon-gil, Seongnam 13620, South Korea. nakim49@snu.ac.kr
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Cohort Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Oct 7, 2019; 25(37): 5619-5629 Published online Oct 7, 2019. doi: 10.3748/wjg.v25.i37.5619
Table 1 Diagnostic criteria of pancreatic cancer
Diagnostic criteria
Methods
Positive finding
Definite criteria
Pathologic analysis
Endoscopy, ERCP, EUS-FNA, Surgery
Adenocarcinoma Mucinous carcinoma Adenosquamous carcinoma Other malignant neoplasm
Possible criteria
Imaging finding
CT, MRI, ERCP, MRCP, EUS, endoscopy, PET
Focal hypo-attenuated lesion Pancreatic duct dilation Distal pancreatic parenchymal atrophy Involvement of the surrounding vascular structures or other organs
Clinical features
Medical record
Clinical courses compatible with PC
Tumor marker
CA19-9
> 100 U/mL
αFP
To exclude other malignancies including hepatocellular carcinoma
Table 4 Diagnostic accuracy of pancreatic cancer diagnosed by the international classification of diseases, 10th revision edition in the administrative database
Status of PC
Total
Positive
Negative
Definite diagnostic criteria
ICD codes of PC
Outcome positive
True positive
False positive
910
904
6
Outcome negative
False negative
True negative
1846
1
1845
Total
905
1851
2756
Possible diagnostic criteria
ICD codes of PC
Outcome positive
True positive
False positive
936
918
18
Outcome negative
False negative
True negative
1846
1
1845
Total
919
1863
2782
Overall diagnostic criteria
ICD codes of PC
Outcome positive
True positive
False positive
1846
1822
24
Outcome negative
False negative
True negative
1846
1
1845
Total
1823
1869
3692
Table 5 Diagnostic accuracy of pancreatic cancer according to tumor sites by the international classification of diseases, 10th revision edition
Table 6 Diagnostic power of international classification of diseases, 10th revision edition for pancreatic cancer
Overall diagnosis
Definite diagnosis
Possible diagnosis
Point estimate (%)
95%CI (%)
Point estimate (%)
95%CI (%)
Point estimate (%)
95%CI (%)
Sensitivity
99.95
99.94-99.95
99.89
99.88-99.90
99.89
99.88-99.90
Specificity
98.72
98.70-98.73
99.68
99.67-99.68
99.03
99.02-99.05
Positive predictive value
98.70
98.68-98.72
99.34
99.32-99.36
98.08
98.05-98.11
Negative predictive value
99.95
99.94-99.95
99.95
99.94-99.95
99.95
99.94-99.95
Citation: Hwang YJ, Park SM, Ahn S, Lee JC, Park YS, Kim N. Accuracy of an administrative database for pancreatic cancer by international classification of disease 10th codes: A retrospective large-cohort study. World J Gastroenterol 2019; 25(37): 5619-5629