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©The Author(s) 2019.
World J Gastroenterol. Apr 14, 2019; 25(14): 1753-1763
Published online Apr 14, 2019. doi: 10.3748/wjg.v25.i14.1753
Published online Apr 14, 2019. doi: 10.3748/wjg.v25.i14.1753
Table 1 Clinical characteristics of the study subjects
CEAS (n = 20) | CD (n = 98) | P value1 | |
Age, yr | 56 (41-63) | 44 (38-54) | 0.098 |
Gender | |||
Male | 5 (25) | 66 (67) | 0.0008 |
Female | 15 (75) | 32 (33) | |
Smoking | |||
Never smoker | 16 (80) | 68 (69) | 0.42 |
Current smoker | 1 (5) | 13 (13) | |
Former smoker | 3 (15) | 17 (18) | |
Pulmonary disease | 1 (5) | 5 (5) | 1 |
History of surgery | 13 (65) | 59 (60) | 0.8 |
CRP, g/dL | 0.30 (0.11-0.53) | 0.13 (0.03-0.58) | 0.26 |
Disease location | |||
L1, ileal | 34 (35) | ||
L2, colonic | 14 (14) | ||
L3, ileocolonic | 50 (51) | ||
Disease duration, yr | 33 (19-42) | 20 (13-29) | 0.0055 |
Table 2 Factors associated with prostaglandin E major urinary metabolite concentrations
Univariable linear regression (P value) | |
Age | P = 0.47 (0.067) |
Gender (1, female; 0, male) | P = 0.26 (0.10) |
Smoking (1, Current or former smoker; 0, Never smoker) | P = 0.17 (-0.13) |
Pulmonary disease | P < 0.0001 (0.36) |
History of surgery | P = 0.029 (0.20) |
CRP | P = 0.078 (0.16) |
Disease duration | P = 0.0040 (0.26) |
Table 3 Convert odds ratio for prostaglandin E major urinary metabolite
Model 1 | Model 2 | Model 3 | |
Odds ratio of 1 log unit change | 7.3 | 6 | 29.6 |
(95%CI) | (3.2-16.7) | (2.6-13.9) | (4.7-185.7) |
AUC (95%CI) | 0.90 (0.82-0.94) | 0.93 (0.87-0.96) | 0.95 (0.86-0.98) |
- Citation: Matsuno Y, Umeno J, Esaki M, Hirakawa Y, Fuyuno Y, Okamoto Y, Hirano A, Yasukawa S, Hirai F, Matsui T, Hosomi S, Watanabe K, Hosoe N, Ogata H, Hisamatsu T, Yanai S, Kochi S, Kurahara K, Yao T, Torisu T, Kitazono T, Matsumoto T. Measurement of prostaglandin metabolites is useful in diagnosis of small bowel ulcerations. World J Gastroenterol 2019; 25(14): 1753-1763
- URL: https://www.wjgnet.com/1007-9327/full/v25/i14/1753.htm
- DOI: https://dx.doi.org/10.3748/wjg.v25.i14.1753