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©The Author(s) 2018.
World J Gastroenterol. Mar 14, 2018; 24(10): 1144-1151
Published online Mar 14, 2018. doi: 10.3748/wjg.v24.i10.1144
Published online Mar 14, 2018. doi: 10.3748/wjg.v24.i10.1144
Table 1 Baseline patient and tumor characteristics n (%)
| Characteristic | Value (n = 51) |
| Number of patients | 51 |
| Sex | |
| Male | 46 (90.2) |
| Female | 5 (9.8) |
| Age, mean ± SD, yr | 63.6 ± 9.4 |
| Comorbidity | |
| Hypertension | 21 (41.2) |
| Diabetes mellitus | 7 (13.7) |
| Chronic kidney disease | 1 (2.0) |
| Smoker | 42 (82.4) |
| Alcohol consumption | 40 (78.4) |
| Gross appearance of tumor | |
| Polypoid | 1 (2.0) |
| Elevated | 8 (15.7) |
| Flat | 40 (78.4) |
| Depressed | 2 (3.9) |
| Location of tumor | |
| Upper third of esophagus | 3 (5.9) |
| Middle third of esophagus | 20 (39.2) |
| Lower third of esophagus | 24 (47.1) |
| Esophagogastric junction | 4 (7.8) |
| Circumferential extension, median (IQR), % | 40 (30-60) |
| Pathology of tumor | |
| Dysplasia | 14 (27.5) |
| Squamous cell carcinoma | 37 (72.5) |
| Invasion depth of tumor | |
| Mucosa | 38 (74.5) |
| Submucosa | 13 (25.5) |
| Resected area, median (IQR), cm2 | 4.5 (2.9-8.2) |
| Procedure time, median (IQR), min | 40 (27-69) |
| Muscle layer exposure | |
| Absent | 27 (52.9) |
| Present | 24 (47.1) |
| En bloc resection | 51 (100) |
| Antibiotics use | 23 (45.1) |
| Post procedure BT, mean ± SD, °C | 36.6 ± 0.5 |
| Post procedure WBC, median (IQR), counts/μL | 10800 (9340-12600) |
| Post procedure pain scale score, median (IQR) | 5 (3-6) |
| Duration of hospitalization, median (IQR), d | 4 (3-6) |
| Post ESD electrocoagulation syndrome | |
| Absent | 18 (35.3) |
| Mild | 24 (47.1) |
| Severe | 9 (17.6) |
Table 2 Univariate analysis of risk factors for post endoscopic submucosal dissection electrocoagulation syndrome n (%)
| No PEECS (n = 18) | PEECS (n = 33) | P value | |
| Male sex, | 17 (94.4) | 29 (87.9) | 0.451 |
| Age, mean ± SD, yr | 63.6 ± 11.2 | 63.6 ± 8.5 | 0.977 |
| Comorbidity | 0.769 | ||
| Absent | 9 (50.0) | 19 (57.6) | |
| Present | 9 (50.0) | 14 (42.4) | |
| Gross appearance | 0.933 | ||
| Flat | 14 (77.8) | 26 (78.8) | |
| Non-flat | 4 (22.2) | 7 (21.2) | |
| Location | 0.378 | ||
| Upper and middle | 10 (55.6) | 13 (39.4) | |
| Lower and EGJ | 8 (44.4) | 20 (60.6) | |
| Circumferential extension, median (IQR), % | 35 (30-42.5) | 40 (30-60) | 0.164 |
| Pathology | 0.487 | ||
| Dysplasia | 6 (33.3) | 8 (24.2) | |
| Squamous cell carcinoma | 12 (66.7) | 25 (75.8) | |
| Invasion depth | 0.082 | ||
| Mucosa | 16 (88.9) | 22 (66.7) | |
| Submucosa | 2 (11.1) | 11 (33.3) | |
| Resected area | 0.035 | ||
| < 6.0 cm2 | 15 (83.3) | 17 (51.5) | |
| ≥ 6.0 cm2 | 3 (16.7) | 16 (48.5) | |
| Procedure time | 0.026 | ||
| < 25 min | 7 (38.9) | 4 (12.1) | |
| ≥ 25 min | 11 (61.1) | 29 (87.9) | |
| Muscle layer exposure | 0.018 | ||
| Absent | 14 (77.8) | 13 (39.4) | |
| Present | 4 (22.2) | 20 (60.6) | |
| Hospitalization period, mean (IQR), d | 3.5 (3-4) | 5 (4-6) | 0.007 |
| Antibiotics use | 0.020 | ||
| No | 14 (77.8) | 14 (42.4) | |
| Yes | 4 (22.2) | 19 (57.6) |
Table 3 Multivariate logistic regression analysis of risk factors for post endoscopic submucosal dissection electrocoagulation syndrome
| Factor | OR (95%CI) | P value |
| Procedure time | 0.379 | |
| ≤ 25 min | Reference | |
| > 25 min | 2.032 (0.419-9.868) | |
| Resected area | 0.036 | |
| ≤ 6.0 cm2 | Reference | |
| > 6.0 cm2 | 4.995 (1.110-22.489) | |
| Muscle layer exposure | 0.014 | |
| Absent | Reference | |
| Present | 5.661 (1.422-22.534) |
- Citation: Ma DW, Youn YH, Jung DH, Park JJ, Kim JH, Park H. Risk factors of electrocoagulation syndrome after esophageal endoscopic submucosal dissection. World J Gastroenterol 2018; 24(10): 1144-1151
- URL: https://www.wjgnet.com/1007-9327/full/v24/i10/1144.htm
- DOI: https://dx.doi.org/10.3748/wjg.v24.i10.1144