Copyright ©The Author(s) 2017.
World J Gastroenterol. Oct 7, 2017; 23(37): 6788-6801
Published online Oct 7, 2017. doi: 10.3748/wjg.v23.i37.6788
Table 1 Prevalence of irritable bowel syndrome in India, Bangladesh and Malaysia
Ref.Study siteSample sizeStudy typeCriteriaPrevalenceMale/female ratio
Shah et al[9]Mumbai, India2549Community/healthy subjectsManning7.5%1/0.87
Ghoshal et al[10]Multiple sites, India4500CommunityClinical4.2%1/0.93
Makharia et al[11]Haryana, India4767CommunityRome III4%1/1.5
Ghoshal et al[12]Uttar Pradesh, India, rural2876CommunityRome III6.8%1/1.09
Masud et al[13]Natore,2426CommunityRome I8.5%1/1.84
Perveen et al[14]Dhaka, Bangladesh, urban1503CommunityRome II7.7%1/1.28
Perveen et al[15]Sylthet,3000CommunityRome III12.9%1/1.09
urban and rural
Rajendra et al[16]West coast, Malaysia, urban1179CommunityRome II14%1/1.4
Lee et al[17]East coast, MalaysiaCommunityRome III10.9%1/1.18
Table 2 Rome III and Rome IV criteria for diagnosis of irritable bowel syndrome[37]
Rome III criteriaRome IV criteria
At least 3 mo, with onset at least 6 mo previous to recurrent (at least 3 d/mo) abdominal pain or discomfort associated with 2 or more of the followingRecurrent abdominal pain, on average, at least 1 d per week in the last 3 mo, associated with 2 or more of the following
Improvement with defecationRelated to defecation
Onset associated with a change of frequency of stoolAssociated with a change in frequency of stool
Onset associated with a change in form of stoolAssociated with a change in form (appearance) of stool
Table 3 Studies on small intestinal bacterial overgrowth in India
Ref.Number of IBS patientsDiagnostic criteria of IBSNumber of controlsMethod of diagnosis of SIBO% of SIBO in IBS% of SIBO in controls
Ghoshal et al[99]80Rome III-Culture of upper jejunal aspirate19-
Rana et al[100]225Rome II100GHBT11.11
Gupta et al[101]69Rome II-GHBT13-
Ghoshal et al[95]129Manning51GHBT8.52
Table 4 Consultation rate of IBS patients in different population-based studies in India and Bangladesh
Ref.Study areas/ countryNumber of IBS patientsDiagnostic criteria of IBSConsultationRateReason of consultationNature of consulting doctors
Shah et al[9]Urban/India190Manning28.94%--
Ghoshal et al[12]Rural/IndiaFGIDsRome III17.20%-MBBS and above (3.1%)
Homeopathic (5%)
Ayuervadic (8.3%)
Unani (0.8%)
Masud et al[13]Rural/Bangladesh593Manning39.0%Altered stool passage
Sense of incomplete evacuation
Mucus in stool
Perveen et al[14]Urban/Bangladesh116Rome II65.50%Multiple dyspeptic symptoms