Retrospective Study
Copyright ©The Author(s) 2017.
World J Gastroenterol. Aug 21, 2017; 23(31): 5809-5816
Published online Aug 21, 2017. doi: 10.3748/wjg.v23.i31.5809
Table 1 Characteristics of the 67 donation after cardiac death donors n (%)
CharacteristicValue
Age in years, median (IQR)29.0 (19.0-44.0)
Sex
Male55 (82.1)
Female12 (17.9)
Origin of death
HT31 (46.3)
Benign CNS tumor18 (26.9)
CVA15 (22.4)
Anoxia2 (3.0)
Meningitis1 (1.5)
China classification of donation
I5 (7.5)
II8 (11.9)
III54 (80.6)
ICU stay in days, median (IQR)5 (3.0-10.0)
Donors with positive culture13
Blood culture, n/n
Donors with/without available results53/14
Donors with appropriate antimicrobial use/all donors with positive blood culture results10/13
Table 2 Classification and percentage of organisms isolated from donors' bloodstream, n = 17
Organismn (%)
Gram-positive bacteria12 (70.6)
Staphylococcus aureus3 (17.6)
Coagulase-negative staphylococci9 (52.9)
S. epidermidis4 (23.5)
S. hemolyticus1 (5.9)
S. capitis1 (5.9)
S. hominis2 (11.8)
S. simulans1 (5.9)
Gram-negative bacteria3 (17.6)
Klebsiella pneumoniae2 (11.8)
Acinetobacter baumannii1 (5.9)
Fungi2 (11.8)
Candida albicans1 (5.9)
Candida parapsilosis1 (5.9)
Table 3 Characteristics of donors and their corresponding liver recipients with donor-derived infections
DonorDiagnosisBlood culture resultRecipient (sex/age)Underlying liver disease(s)Culture result (specimen)/time to infection onsetInappropriate antimicrobial/immunosuppressive therapyOutcome
D1Head traumaNegative1R12 (Female/48 yr)Polycystic liver diseaseK. pneumoniae (Blood and abdominal drainage fluid)/1 dNo/PredPatient death and graft loss
D2Head traumaNegative1R23 (Male/38 yr)Hepatocellular carcinoma and cirrhosis due to hepatitis B virus infectionK. pneumoniae (Blood and abdominal drainage fluid)/1 dNo/FK506 + PredPatient and graft survival
D3Head traumaNot availableR33 (Male/69 yr)Heredofamilial amyloidosisE. aerogenes (Blood)/3 dNo/FK506 + PredPatient and graft survival
Table 4 Comparison of post-liver-transplant complications in liver recipients with and without donor-derived infections
ComplicationEpisodes of complications in three liver recipients with donor-derived infectionsEpisodes of complications in 64 liver recipients without donor-derived infections
Infection416
Pneumonia17
Peritonitis03
Bloodstream infection35
Surgical site infection01
Vascular complications09
Portal vein thrombosis01
Cerebral embolism01
Hepatic artery thrombosis01
Abdominal bleeding05
Gastrointestinal bleeding01
Biliary complications32
Bile leakage00
Biliary strictures12
Stone formation10
Bilomas10
Recurrent tumor06
Acute rejection04
Graft-versus-host disease02
Graft dysfunction03
Adhesive ileus01