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©The Author(s) 2017.
World J Gastroenterol. Jun 21, 2017; 23(23): 4262-4269
Published online Jun 21, 2017. doi: 10.3748/wjg.v23.i23.4262
Published online Jun 21, 2017. doi: 10.3748/wjg.v23.i23.4262
Table 1 Prevalence of colorectal neoplasm in the endoscopic submucosal dissection group n (%)
Colorectal neoplasm | ESD group (n = 158) |
Non-lesion | 78 (49.4) |
Adenoma (< 1 cm) | 53 (33.5) |
Advanced adenoma | 17 (10.8) |
Large tubular adenoma (≥ 1 cm) | |
Tubulovillous/villous adenoma | |
High grade dysplasia | |
Early cancer (depth of mucosa/submucosa) | 5 (3.2) |
Advanced cancer | 4 (2.5) |
Neuroendocrine tumor | 1 (0.6) |
Table 2 Comparison of characteristics between endoscopic submucosal dissection group and fecal immunochemical test group n (%)
ESD group (n = 158) | FIT group (n = 158) | P value | |
Age (year, mean ± SD) | 69.5 ± 8.9 | 69.5 ± 8.9 | 0.999 |
Gender, male/female | 130 (82.3)/28 (17.7) | 130 (82.3)/28 (17.7) | 0.999 |
BMI (kg/m2) | 23.0 ± 3.1 | 22.8 ± 3.4 | 0.589 |
Smoking | 100 (63.0) | 86 (54.4) | 0.137 |
Alcohol | 74 (46.8) | 66 (41.8) | 0.428 |
Diabetes mellitus | 20 (12.7) | 27 (17.1) | 0.343 |
Dyslipidemia | 25 (15.8) | 40 (25.3) | 0.051 |
Hypertension | 73 (46.2) | 88 (55.7) | 0.115 |
History of other organs’ cancer | 24 (15.2) | 17 (10.8) | 0.315 |
Table 3 Comparison of prevalence of colorectal neoplasm between endoscopic submucosal dissection group and fecal immunochemical test group n (%)
Colorectal neoplasm | ESD group (n = 158) | FIT group (n = 158) | P value |
Adenoma (< 1 cm) | 53 (33.5) | 66 (41.8) | 0.164 |
Advanced adenoma | 17 (10.8) | 24 (15.2) | 0.315 |
Large tubular adenoma (≥ 1 cm) | |||
Tubulovillous/villous adenoma | |||
High grade dysplasia | |||
Number of adenomas | 0.507 | ||
1 to 3 | 59 (37.3) | 71 (44.9) | |
≥ 4 | 11 (7.0) | 19 (12.0) | |
Cancer or NET | 10 (6.3) | 10 (6.3) | 0.999 |
Table 4 Analysis of risk factors related to colorectal neoplasm in gastric endoscopic submucosal dissection patients n (%)
CRN group (n = 80) | Non-CRN group (n = 78) | P value | |
Gender, male/female | 71 (88.8)/9 (11.3) | 59 (75.6)/19 (24.4) | 0.031 |
Age (yr, mean ± SD) | 70.8 ± 8.3 | 68.9 ± 10.4 | 0.215 |
Histopathology (adenoma/carcinoma) | 69 (86.3)/11 (13.8) | 70 (89.7)/8 (10.3) | 0.667 |
Tumor size (mm, mean ± SD) | 19.3 ± 12.3 | 19.0 ± 17.2 | 0.926 |
Tumor location | |||
U | 17 (21.3) | 16 (20.5) | 0.999 |
M | 33 (41.3) | 28 (35.9) | 0.598 |
L | 30 (37.5) | 34 (43.6) | 0.538 |
BMI | 23.3 ± 3.3 | 22.7 ± 2.8 | 0.219 |
Lifestyle related disease1 | 16 (20.0) | 13 (16.7) | 0.737 |
Smoking | 55 (68.8) | 45 (57.7) | 0.202 |
Alcohol | 41 (51.3) | 33 (42.3) | 0.334 |
History of other organs’ cancer | 16 (20.0) | 9 (11.5) | 0.215 |
Table 5 Analysis of risk factors related to advanced adenoma and carcinoma in gastric endoscopic submucosal dissection patients
AAC group (n = 26) | Non-AAC group (n = 132) | P value | |
Gender, male/female | 23 (88.5)/3 (11.5) | 107 (81.1)/25 (18.9) | 0.574 |
Age (yr, mean ± SD) | 70.4 ± 8.5 | 69.7 ± 9.6 | 0.732 |
Histopathology (adenoma/carcinoma) | 6 (23.1)/20 (76.9) | 13 (9.85/119 (90.2) | 0.117 |
Tumor size (mm, mean ± SD) | 21.9 ± 12.5 | 18.6 ± 12.7 | 0.305 |
Tumor location | |||
U | 4 (15.4) | 29 (22.0) | 0.601 |
M | 13 (50.0) | 48 (36.4) | 0.278 |
L | 9 (34.6) | 55 (41.7) | 0.652 |
BMI | 23.9 ± 3.8 | 22.8 ± 2.9 | 0.074 |
Lifestyle related disease1 | 9 (34.6) | 20 (15.2) | 0.019 |
Smoking | 20 (76.9) | 80 (60.6) | 0.175 |
Alcohol | 15 (57.7) | 59 (44.7) | 0.318 |
History of other organs’ cancer | 6 (23.1) | 19 (14.4) | 0.415 |
Table 6 Multivariate logistic regression analyses for risk ratio of overall colorectal neoplasm, and advanced adenoma and carcinoma in gastric endoscopic submucosal dissection patients
Overall colorectal neoplasm | AAC | |||
OR (95%CI) | P value | OR (95%CI) | P value | |
Age (≥ 65 yr) | 1.42 (0.68-3.00) | 0.350 | 0.70 (0.27-1.82) | 0.460 |
Gender (male) | 2.65 (1.11-6.36) | 0.029 | 1.85 (0.49-6.97) | 0.362 |
BMI (≥ 25) | 1.21 (0.57-2.56) | 0.613 | 1.80 (0.71-4.58) | 0.217 |
Lifestyle related disease1 | 1.24 (0.54-2.85) | 0.608 | 3.01 (1.16-7.86) | 0.024 |
- Citation: Tsuchida C, Yoshitake N, Kino H, Kaneko Y, Nakano M, Tsuchida K, Tominaga K, Sasai T, Masuyama H, Yamagishi H, Imai Y, Hiraishi H. Clinical importance of colonoscopy in patients with gastric neoplasm undergoing endoscopic submucosal dissection. World J Gastroenterol 2017; 23(23): 4262-4269
- URL: https://www.wjgnet.com/1007-9327/full/v23/i23/4262.htm
- DOI: https://dx.doi.org/10.3748/wjg.v23.i23.4262