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©The Author(s) 2017.
World J Gastroenterol. Mar 28, 2017; 23(12): 2201-2208
Published online Mar 28, 2017. doi: 10.3748/wjg.v23.i12.2201
Published online Mar 28, 2017. doi: 10.3748/wjg.v23.i12.2201
Table 1 Demographic information of LC[Pos] and LC[Neg] patients n (%)
Variables | LC[Pos] patients(n = 5551) | LC[Neg] patients(n = 11102) | P value |
Gender | 0.99 | ||
Male | 3655 (65.84) | 7311 (65.85) | |
Female | 1896 (34.16) | 3791 (34.15) | |
Age group (yr) | 0.59 | ||
< 50 | 1259 (22.68) | 2417 (21.77) | |
50-64 | 1441 (25.96) | 2899 (26.11) | |
65-79 | 1914 (34.48) | 3902 (35.15) | |
≥ 80 | 937 (16.88) | 1884 (16.97) | |
Department | < 0.01a | ||
Surgical | 542 (9.76) | 1684 (15.17) | |
Medical | 5009 (90.24) | 9418 (84.83) | |
Number of organ failures | < 0.01a | ||
0 | 3404 (61.32) | 8433 (75.96) | |
1 | 1791 (32.26) | 2415 (21.75) | |
≥ 2 | 356 (6.41) | 254 (2.29) | |
Comorbidity | |||
DM | 2048 (36.89) | 4082 (36.77) | 0.87 |
HTN | 2454 (44.21) | 4895 (44.09) | 0.89 |
CAD | 1077 (19.40) | 2144 (19.31) | 0.89 |
ESRD | 627 (11.30) | 1287 (11.59) | 0.57 |
COPD | 1133 (20.41) | 2277 (20.51) | 0.88 |
Cancer | 1362 (24.54) | 2739 (24.67) | 0.85 |
Stroke | 980 (17.65) | 1944 (17.51) | 0.82 |
CHF | 784 (14.12) | 1547 (13.93) | 0.74 |
HBV | 14 (0.25) | 28 (0.25) | 1.00 |
HCV | 21 (0.38) | 35 (0.32) | 0.51 |
Cryptogenic LC[Pos] | 1732 (31.20) |
Table 2 Adjusted hazard ratios for mortality in patients after their 1st-ever mechanical ventilation n (%)
No. of deaths | LC[Pos] patients(n = 5551) | LC[Neg] patients(n = 11102) | Adjusted hazard ratio(95%CI) |
Overall | 3747 (67.50) | 5902 (53.16) | 1.38 (1.32-1.44)a |
Age (yr) | |||
< 50 | 763 (13.75) | 744 (6.70) | 1.96 (1.76-2.18)a |
50-64 | 911 (16.41) | 1369 (12.33) | 1.40 (1.29-1.53)a |
65-79 | 1368 (24.64) | 2458 (22.14) | 1.24 (1.16-1.32)a |
≥ 80 | 705 (12.70) | 1331 (11.99) | 1.41 (1.04-1.25)a |
Gender | |||
Male | 2464 (44.39) | 3770 (33.96) | 1.42 (1.35-1.49)a |
Female | 1283 (23.11) | 2132 (19.20) | 1.30 (1.21-1.39)a |
Department | |||
Surgical | 255 (4.59) | 595 (5.36) | 1.32 (1.14-1.54)a |
Medical | 3492 (62.91) | 5307 (47.80) | 1.37 (1.31-1.43)a |
Number of organ failures | |||
0 | 2074 (37.36) | 4015 (36.16) | 1.40 (1.33-1.47)a |
1 | 1379 (24.84) | 1691 (15.23) | 1.26 (1.17-1.35)a |
≥ 2 | 294 (5.30) | 196 (1.77) | 1.16 (0.96-1.41) |
Comorbidity | |||
DM | 1374 (24.75) | 2432 (21.91) | 1.19 (1.12-1.28)a |
HTN | 1583 (28.52) | 2851 (25.68) | 1.15 (1.08-1.22)a |
CAD | 716 (12.90) | 1276 (11.49) | 1.17 (1.07-1.28)a |
ESRD | 488 (8.79) | 920 (8.29) | 1.19 (1.06-1.33)a |
COPD | 789 (14.21) | 1459 (13.14) | 1.15 (1.05-1.26)a |
Cancer | 972 (17.51) | 1668 (15.02) | 1.31 (1.21-1.42)a |
Stroke | 680 (12.25) | 1261 (11.36) | 1.16 (1.06-1.28)a |
CHF | 563 (10.14) | 1002 (9.03) | 1.21 (1.09-1.34)a |
HBV | 7 (0.13) | 12 (0.11) | 0.54 (0.11-2.57) |
HCV | 11 (0.20) | 20 (0.18) | 0.43 (0.14-1.28) |
Table 3 Hazard ratio of mortality risk for patients with non-cryptogenic liver cirrhosis, cryptogenic liver cirrhosis, and liver cirrhosis[Neg] patients after 1st-ever mechanical ventilation, stratified by gender and age group
LC[Neg] | Cryptogenic LC[Pos] | Non-cryptogenic LC[pos] | |
Overall | 1.00 (ref.) | 1.05 (0.98-1.12) | 1.56 (1.49-1.63)a |
Patients with LC only | 1.00 (ref.) | 1.43 (1.32-1.54)a | |
Males only | |||
Overall | 1.00 (ref.) | 1.06 (0.97-1.16) | 1.58 (1.49-1.67)a |
Patients with LC only | 1.00 (ref.) | 1.40 (1.27-1.55)a | |
Females only | |||
Overall | 1.00 (ref.) | 1.02 (0.92-1.13) | 1.52 (1.40-1.64)a |
Patients with LC only | 1.00 (ref.) | 1.48 (1.31-1.67)a | |
Age group: < 50 | |||
Overall | 1.00 (ref.) | 1.31 (1.07-1.60)a | 2.17 (1.94-2.43)a |
Patients with LC only | 1.00 (ref.) | 1.68 (1.36-2.08)a | |
Age group: 50-64 | |||
Overall | 1.00 (ref.) | 0.96 (0.82-1.13) | 1.59 (1.44-1.74)a |
Patients with LC only | 1.00 (ref.) | 1.70 (1.42-2.03)a | |
Age group: 65-79 | |||
Overall | 1.00 (ref.) | 1.07 (0.96-1.18) | 1.35 (1.25-1.46)a |
Patients with LC only | 1.00 (ref.) | 1.27 (1.13-1.43)a | |
Age group: ≥ 80 | |||
Overall | 1.00 (ref.) | 0.92 (0.80-1.06) | 1.31 (1.17-1.45)a |
Patients with LC only | 1.00 (ref.) | 1.40 (1.19-1.64)a |
- Citation: Lai CC, Ho CH, Cheng KC, Chao CM, Chen CM, Chou W. Effect of liver cirrhosis on long-term outcomes after acute respiratory failure: A population-based study. World J Gastroenterol 2017; 23(12): 2201-2208
- URL: https://www.wjgnet.com/1007-9327/full/v23/i12/2201.htm
- DOI: https://dx.doi.org/10.3748/wjg.v23.i12.2201